HitPredict

Interactor 1: NT2NA (Q7Z3S9)
Notch homolog 2 N-terminal-like protein A (Notch homolog 2 N-terminal-like protein)
Gene: NOTCH2NLA

Interactor 2: SEM4C (Q9C0C4)
Semaphorin-4C
Gene: SEMA4C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	25416956, 32296183
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007411 - axon guidance GO:0050919 - negative chemotaxis
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 236 Hs			1 833
+	Hs
		484709 NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95		SEM4C_HUMAN (1-833): 0: 951: 100.00
+	Hs
		1027971 NT2NA_HUMAN (1-236): 1e-44: 151: 100.00		SEM3B_HUMAN (12-718): 0: 650: 31.51
+	Hs
		484601 NT2NC_HUMAN (69-233): 8.71e-14: 70.8: 32.95		SEM3B_HUMAN (12-718): 0: 650: 31.51
+	Dm
		706607 FAT_DROME (145-236): 1.12e-20: 92.4: 24.17		Q0E8S4_DROME (5-564): 1.08e-174: 529: 31.03
+	Dm
		706611 FAT_DROME (145-236): 1.12e-20: 92.4: 24.17		SEM1A_DROME (5-564): 9.1e-175: 529: 31.03
+	Dm
		246772 TENM_DROME (2-124): 1.24e-14: 74.7: 17.71		Q0E8S4_DROME (5-564): 1.08e-174: 529: 31.03
+	Dm
		246787 TENM_DROME (2-124): 1.24e-14: 74.7: 17.71		SEM1A_DROME (5-564): 9.1e-175: 529: 31.03
+	Dm
		1000847 FAT2_DROME (50-114): 4.2e-10: 61.2: 28.36		Q0E8S4_DROME (5-564): 1.08e-174: 529: 31.03
+	Dm
		1097435 FAT2_DROME (50-114): 4.2e-10: 61.2: 28.36		SEM1A_DROME (5-564): 9.1e-175: 529: 31.03