HitPredict

Interactor 1: MAVS (Q7Z434)
Mitochondrial antiviral-signaling protein (MAVS) (CARD adapter inducing interferon beta) (Cardif) (Interferon beta promoter stimulator protein 1) (IPS-1) (Putative NF-kappa-B-activating protein 031N) (Virus-induced-signaling adapter) (VISA)
Gene: MAVS

Interactor 2: MTCH2 (Q9Y6C9)
Mitochondrial carrier homolog 2 (Met-induced mitochondrial protein)
Gene: MTCH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32877691
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0070585 - protein localization to mitochondrion
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 540 Hs			1 303
+	Hs
		1190114 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		MTCH1_HUMAN (8-295): 1.79e-108: 322: 46.89
+	Hs
		274569 MAVS_HUMAN (1-540): 1.73e-73: 245: 100.00		S2512_HUMAN (4-115): 2e-18: 87.3: 14.29
+	Hs
		518401 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		ADT3_HUMAN (113-299): 3.27e-29: 114: 14.00
+	Hs
		397430 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		ADT2_HUMAN (113-299): 1.34e-28: 113: 13.50
+	Hs
		518162 MICA3_HUMAN (68-506): 7.25e-20: 96: 12.82		ADT1_HUMAN (113-299): 2e-28: 112: 13.78
+	Hs
		1192222 HUWE1_HUMAN (79-539): 8.05e-24: 108: 13.36		TPC_HUMAN (1-100): 8.86e-21: 92.3: 22.00
+	Hs
		518459 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		ADT3_HUMAN (113-299): 3.27e-29: 114: 14.00
+	Hs
		397479 CIC_HUMAN (40-516): 7.01e-10: 64.1: 12.58		ADT2_HUMAN (113-299): 1.34e-28: 113: 13.50