Interactor 1: TPPC3 (O43617)
Trafficking protein particle complex subunit 3 (BET3 homolog)
Gene: TRAPPC3

Interactor 2: TPPC1 (Q9Y5R8)
Trafficking protein particle complex subunit 1 (BET5 homolog) (Multiple myeloma protein 2) (MUM-2)
Gene: TRAPPC1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.971

The method score is based on:

Property Details
Experiments 28514442, 27173435, 33961781, 35271311, 21525244, 32296183, 11805826, 16828797, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, tandem affinity purification, pull down, two hybrid array, two hybrid prey pooling approach, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Sybindin~TRAPP
Common GO terms GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006901 - vesicle coating
and 5 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 180
Hs

1 145
+ Mm
+ Hs
+ Hs
+ Hs
+ Dm
+ Sc
+ Ce
+ Sc

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Last updated: 15 Jul 2024