HitPredict

Interactor 1: Q3UJF1 (Q3UJF1)
Histone deacetylase (EC 3.5.1.98)
Gene: Hdac5

Interactor 2: MEF2D (Q63943)
Myocyte-specific enhancer factor 2D
Gene: MEF2D

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	10737771
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0042826 - histone deacetylase binding GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1115 Mm			1 514
+	Mm
		1224655 HDAC5_MOUSE (1-1115): 0: 769: 99.28		MEF2D_MOUSE (1-514): 7.66e-88: 281: 100.00
+	Mm
		1190328 Q3UJF1_MOUSE (1-1115): 0: 778: 100.00		MEF2A_MOUSE (1-511): 9.85e-83: 267: 51.79
+	Mm
		1190342 Q3UJF1_MOUSE (1-1115): 0: 778: 100.00		MEF2C_MOUSE (1-508): 3.48e-77: 251: 50.20
+	Hs
		1132677 HDAC5_HUMAN (1-1115): 0: 742: 93.42		MEF2D_HUMAN (1-514): 3.14e-86: 277: 93.47
+	Hs
		1034706 HDAC5_HUMAN (1-1115): 0: 742: 93.42		MEF2A_HUMAN (1-511): 2.29e-82: 266: 49.63
+	Hs
		1055037 HDAC5_HUMAN (1-1115): 0: 742: 93.42		MEF2C_HUMAN (1-508): 2.1e-76: 250: 50.00
+	Mm
		1224651 HDAC4_MOUSE (3-1096): 0: 687: 54.65		MEF2D_MOUSE (1-514): 7.66e-88: 281: 100.00
+	Mm
		1221965 HDAC4_MOUSE (3-1096): 0: 687: 54.65		MEF2A_MOUSE (1-511): 9.85e-83: 267: 51.79
+	Hs
		940965 HDAC4_HUMAN (3-1095): 0: 677: 56.10		MEF2D_HUMAN (1-514): 3.14e-86: 277: 93.47
+	Rn
		313313 HDAC4_RAT (3-1096): 0: 681: 54.83		MEF2D_RAT (1-514): 1.3e-83: 269: 97.86
+	Hs
		940921 HDAC4_HUMAN (3-1095): 0: 677: 56.10		MEF2A_HUMAN (1-511): 2.29e-82: 266: 49.63
+	Mm
		1240099 HDAC4_MOUSE (3-1096): 0: 687: 54.65		MEF2C_MOUSE (1-508): 3.48e-77: 251: 50.20
+	Hs
		940928 HDAC4_HUMAN (3-1095): 0: 677: 56.10		MEF2C_HUMAN (1-508): 2.1e-76: 250: 50.00
+	Hs
		1034705 HDAC9_HUMAN (26-1048): 0: 629: 55.32		MEF2A_HUMAN (1-511): 2.29e-82: 266: 49.63
+	Hs
		549303 HDAC4_HUMAN (3-1095): 0: 677: 56.10		SRF_HUMAN (2-434): 9.42e-62: 212: 17.39
+	Hs
		1055036 HDAC9_HUMAN (26-1048): 0: 629: 55.32		MEF2C_HUMAN (1-508): 2.1e-76: 250: 50.00
+	Hs
		940922 HDAC4_HUMAN (3-1095): 0: 677: 56.10		MEF2B_HUMAN (1-123): 3.44e-34: 134: 71.55
+	Hs
		1034694 HDAC7_HUMAN (113-1115): 3.01e-162: 507: 39.96		MEF2A_HUMAN (1-511): 2.29e-82: 266: 49.63
+	Hs
		1034718 HDAC9_HUMAN (26-1048): 0: 629: 55.32		MEF2B_HUMAN (1-123): 3.44e-34: 134: 71.55
+	Ce
		196030 HDA4_CAEEL (299-1070): 1.04e-179: 549: 31.19		MEF2_CAEEL (1-114): 3.38e-40: 150: 74.56