HitPredict - High confidence protein-protein interactions

Interactor 1: WAPL (Q7Z5K2)
Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)
Gene: WAPL

Interactor 2: WAPL (Q7Z5K2)
Wings apart-like protein homolog (Friend of EBNA2 protein) (WAPL cohesin release factor)
Gene: WAPL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.90	0.811

Property	Details
Experiments	31010829, 35271311, 20360068
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WAPL~WAPL
Common GO terms	GO:0000070 - mitotic sister chromatid segregation GO:0000775 - chromosome, centromeric region GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm and 13 others more... GO:0005694 - chromosome GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0008156 - negative regulation of DNA replication GO:0035562 - negative regulation of chromatin binding GO:0043231 - intracellular membrane-bounded organelle GO:0045171 - intercellular bridge GO:0045875 - negative regulation of sister chromatid cohesion GO:0051301 - cell division GO:0071168 - protein localization to chromatin GO:0071922 - regulation of cohesin loading GO:0072686 - mitotic spindle GO:0140083 - ATP-dependent protein-DNA unloader activity
Homologous interactions	0

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Last updated: 15 Jul 2024