HitPredict

Interactor 1: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Interactor 2: UBP7 (Q93009)
Ubiquitin carboxyl-terminal hydrolase 7 (EC 3.4.19.12) (Deubiquitinating enzyme 7) (Herpesvirus-associated ubiquitin-specific protease) (Ubiquitin thioesterase 7) (Ubiquitin-specific-processing protease 7)
Gene: USP7

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.87 1.00 0.933

The method score is based on:

Property Details
Experiments 27452404, 30367141, 17651432, 36243803, 31839598, 16111684
Identification Methods unspecified method, affinity chromatography technology, biochemical, pull down, cross-linking study, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains MATH_2~MATH_2, UCH~UCH, UCH~USP7_C2, USP7_C2~USP7_C2, USP7_C2~USP7_ICP0_bdg, USP7_ICP0_bdg~USP7_ICP0_bdg
Common GO terms GO:0002039 - p53 binding
GO:0004197 - cysteine-type endopeptidase activity
GO:0004843 - cysteine-type deubiquitinase activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 28 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

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Hs

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Last updated: 11Aug2025