HitPredict

Interactor 1: GRDN (Q3V6T2)
Girdin (Akt phosphorylation enhancer) (APE) (Coiled-coil domain-containing protein 88A) (G alpha-interacting vesicle-associated protein) (GIV) (Girders of actin filament) (Hook-related protein 1) (HkRP1)
Gene: CCDC88A

Interactor 2: RHOV (Q96L33)
Rho-related GTP-binding protein RhoV (CDC42-like GTPase 2) (GTP-binding protein-like 2) (Rho GTPase-like protein ARHV) (Wnt-1 responsive Cdc42 homolog 2) (WRCH-2)
Gene: RHOV

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0007264 - small GTPase-mediated signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1871 Hs			1 236
+	Hs
		1191433 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RHOU_HUMAN (32-236): 2.91e-89: 265: 60.48
+	Hs
		988410 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		601313 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RHOQ_HUMAN (23-236): 1.98e-75: 228: 50.00
+	Hs
		953479 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		581085 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		962112 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		1015483 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		955239 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39
+	Hs
		1191484 GRDN_HUMAN (1-1871): 1.42e-146: 501: 100.00		RHOJ_HUMAN (32-214): 8.34e-59: 186: 50.27
+	Hs
		962582 DAPLE_HUMAN (3-1838): 2.67e-101: 365: 45.75		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		772724 MYH9_HUMAN (1117-1871): 5.15e-30: 132: 9.12		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		772743 MYH9_HUMAN (1117-1871): 5.15e-30: 132: 9.12		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		776848 MYH11_HUMAN (8-729): 4.33e-25: 116: 13.32		RHOV_HUMAN (1-236): 1.28e-77: 235: 100.00
+	Hs
		773156 MYH10_HUMAN (10-690): 3.42e-24: 113: 12.94		RHOG_HUMAN (30-210): 9.78e-73: 221: 49.17
+	Hs
		157213 CTRO_HUMAN (929-1402): 1.03e-18: 95.8: 16.77		RAC1_HUMAN (32-217): 7.38e-78: 234: 53.23
+	Hs
		157196 CTRO_HUMAN (929-1402): 1.03e-18: 95.8: 16.77		RAB1A_HUMAN (22-234): 7.35e-76: 229: 21.10
+	Hs
		953426 GOGA4_HUMAN (1-648): 1e-18: 95.8: 9.54		RAC3_HUMAN (32-206): 8.74e-75: 226: 56.00
+	Hs
		581025 GOGA4_HUMAN (1-648): 1e-18: 95.8: 9.54		RAC2_HUMAN (32-216): 1.84e-74: 225: 52.43
+	Hs
		157168 CTRO_HUMAN (929-1402): 1.03e-18: 95.8: 16.77		RHOA_HUMAN (33-215): 4.5e-74: 224: 42.62
+	Hs
		773143 MYH10_HUMAN (10-690): 3.42e-24: 113: 12.94		CDC42_HUMAN (32-207): 2.13e-66: 205: 57.39