HitPredict

Interactor 1: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Interactor 2: CDK15 (Q96Q40)
Cyclin-dependent kinase 15 (EC 2.7.11.22) (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 7 protein) (Cell division protein kinase 15) (Serine/threonine-protein kinase ALS2CR7) (Serine/threonine-protein kinase PFTAIRE-2)
Gene: CDK15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29845934
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Pkinase~RRM_1
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 582 Hs			1 435
+	Hs
		667893 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK2_HUMAN (100-398): 4.22e-139: 401: 47.51
+	Hs
		1025269 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK3_HUMAN (100-405): 1.21e-136: 395: 48.38
+	Hs
		322106 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK14_HUMAN (17-427): 1.35e-130: 386: 55.85
+	Hs
		1025552 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK16_HUMAN (16-429): 5.18e-129: 383: 44.44
+	Hs
		1025622 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK17_HUMAN (17-429): 9.59e-129: 383: 43.57
+	Hs
		443393 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK1_HUMAN (100-391): 1.32e-129: 377: 45.09
+	Hs
		1025468 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK5_HUMAN (100-393): 9.95e-129: 375: 50.00
+	Hs
		1057615 LARP7_HUMAN (1-582): 4.06e-128: 389: 100.00		CDK18_HUMAN (44-424): 3.41e-125: 373: 47.77
+	Hs
		430990 LA_HUMAN (24-365): 5.99e-44: 163: 18.83		CDK2_HUMAN (100-398): 4.22e-139: 401: 47.51
+	Hs
		550125 PABP1_HUMAN (1-405): 7.87e-41: 158: 10.29		CDK2_HUMAN (100-398): 4.22e-139: 401: 47.51
+	Sc
		602386 LHP1_YEAST (7-270): 1.35e-45: 163: 22.74		PHO85_YEAST (100-389): 1.32e-129: 378: 50.17
+	Hs
		1057640 LAR4B_HUMAN (2-216): 8.51e-36: 145: 17.02		CDK18_HUMAN (44-424): 3.41e-125: 373: 47.77
+	Dm
		620686 SXL_DROME (59-259): 1.13e-24: 107: 20.29		CDK2_DROME (99-402): 2.74e-127: 372: 43.46
+	Dm
		120668 LARP_DROME (38-120): 1.59e-13: 76.1: 35.23		M9PE01_DROME (8-416): 1.09e-130: 389: 51.20
+	At
		1423179 PABP8_ARATH (2-127): 4.11e-15: 80.7: 11.91		CDKD2_ARATH (91-432): 1.01e-128: 377: 38.78
+	Hs
		443377 ELAV1_HUMAN (92-211): 7.75e-13: 71.9: 22.50		CDK1_HUMAN (100-391): 1.32e-129: 377: 45.09
+	Sc
		364209 PABP_YEAST (9-243): 4.77e-33: 135: 13.47		CDK1_YEAST (98-387): 2.01e-81: 254: 47.81