HitPredict

Interactor 1: RD23B (Q4KMA2)
UV excision repair protein RAD23 homolog B
Gene: Rad23b

Interactor 2: Q5HZY3 (Q5HZY3)
Ubiquitin carboxyl-terminal hydrolase (EC 3.4.19.12)
Gene: Uchl5

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	19182904
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Peptidase_C12~ubiquitin, UCH_C~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0070628 - proteasome binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 415 Rn			1 324
+	Hs
		931729 RD23B_HUMAN (1-415): 1.02e-116: 348: 86.51		UCHL5_HUMAN (1-316): 4.18e-170: 477: 97.15
+	Hs
		931629 RD23A_HUMAN (1-415): 7.4e-94: 288: 54.46		UCHL5_HUMAN (1-316): 4.18e-170: 477: 97.15
+	Hs
		1462106 UBQL1_HUMAN (1-410): 2.54e-64: 218: 13.60		UCHL5_HUMAN (1-316): 4.18e-170: 477: 97.15
+	Mm
		509325 UBC_MOUSE (1-110): 8.29e-31: 126: 23.64		UCHL5_MOUSE (1-316): 8.11e-172: 481: 99.05
+	Dm
		583729 RS27A_DROME (1-75): 4.58e-16: 76.9: 32.00		Q9XZ61_DROME (1-316): 1.08e-144: 412: 61.51
+	Hs
		583905 UBQL1_HUMAN (1-410): 2.54e-64: 218: 13.60		UCHL3_HUMAN (4-226): 3.42e-87: 263: 26.61
+	Hs
		931689 RD23B_HUMAN (1-415): 1.02e-116: 348: 86.51		BAP1_HUMAN (252-322): 4.58e-16: 80.9: 36.62
+	Dm
		583681 RS27A_DROME (1-75): 4.58e-16: 76.9: 32.00		CALYP_DROME (1-315): 1.57e-117: 348: 33.15
+	Mm
		509299 UBC_MOUSE (1-110): 8.29e-31: 126: 23.64		UCHL3_MOUSE (4-226): 2e-87: 263: 27.04
+	Hs
		507066 UBB_HUMAN (1-80): 6.02e-31: 120: 30.00		UCHL3_HUMAN (4-226): 3.42e-87: 263: 26.61
+	Hs
		583873 Q5U5U6_HUMAN (1-80): 6.02e-31: 120: 30.00		UCHL3_HUMAN (4-226): 3.42e-87: 263: 26.61
+	Mm
		508999 UBC_MOUSE (1-110): 8.29e-31: 126: 23.64		UCHL4_MOUSE (4-226): 1e-83: 254: 26.70
+	Hs
		931573 RD23A_HUMAN (1-415): 7.4e-94: 288: 54.46		BAP1_HUMAN (252-322): 4.58e-16: 80.9: 36.62
+	Hs
		488379 UBB_HUMAN (1-80): 6.02e-31: 120: 30.00		UCHL1_HUMAN (10-226): 9.88e-77: 236: 21.78
+	Mm
		509316 UBC_MOUSE (1-110): 8.29e-31: 126: 23.64		UCHL1_MOUSE (10-226): 2.14e-74: 230: 22.22
+	Hs
		583868 NEDD8_HUMAN (1-64): 8.13e-15: 71.1: 37.50		UCHL3_HUMAN (4-226): 3.42e-87: 263: 26.61
+	Sc
		509887 RL40A_YEAST (1-111): 3.41e-37: 133: 22.52		UBL1_YEAST (1-226): 3.8e-61: 196: 24.79
+	Hs
		488443 RS27A_HUMAN (1-91): 4.32e-16: 76.9: 26.37		UCHL1_HUMAN (10-226): 9.88e-77: 236: 21.78
+	Hs
		488482 NEDD8_HUMAN (1-64): 8.13e-15: 71.1: 37.50		UCHL1_HUMAN (10-226): 9.88e-77: 236: 21.78
+	Hs
		987140 RS27A_HUMAN (1-91): 4.32e-16: 76.9: 26.37		BAP1_HUMAN (252-322): 4.58e-16: 80.9: 36.62