HitPredict

Interactor 1: Q53FC7 (Q53FC7)
Heat shock 70 kDa protein 6
Gene: Q53FC7

Interactor 2: BAG5 (Q9UL15)
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)
Gene: BAG5

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	25036637
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 643 Hs			1 447
+	Hs
		600958 HSP76_HUMAN (1-643): 0: 986: 99.22		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Hs
		761536 HS71L_HUMAN (1-643): 0: 976: 78.85		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Mm
		609027 HS71B_MOUSE (5-643): 0: 955: 80.31		BAG5_MOUSE (1-447): 0: 758: 91.28
+	Mm
		989273 HSP7C_MOUSE (4-615): 0: 953: 78.76		BAG5_MOUSE (1-447): 0: 758: 91.28
+	Hs
		538096 HSP7C_HUMAN (4-615): 0: 953: 78.76		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Hs
		336621 HSP76_HUMAN (1-643): 0: 986: 99.22		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347515 HSP76_HUMAN (1-643): 0: 986: 99.22		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336682 Q53FC7_HUMAN (1-643): 0: 981: 100.00		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347739 Q53FC7_HUMAN (1-643): 0: 981: 100.00		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336630 HS71L_HUMAN (1-643): 0: 976: 78.85		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347555 HS71L_HUMAN (1-643): 0: 976: 78.85		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Mm
		609028 HS71B_MOUSE (5-643): 0: 955: 80.31		BAG4_MOUSE (363-441): 1.06e-29: 122: 44.30
+	Hs
		336616 HSP7C_HUMAN (4-615): 0: 953: 78.76		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347494 HSP7C_HUMAN (4-615): 0: 953: 78.76		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Mm
		609032 HS71B_MOUSE (5-643): 0: 955: 80.31		BAG3_MOUSE (361-442): 1.13e-27: 117: 45.88
+	Mm
		989288 HSP7C_MOUSE (4-615): 0: 953: 78.76		BAG3_MOUSE (361-442): 1.13e-27: 117: 45.88
+	Hs
		347489 HS71A_HUMAN (5-643): 0: 949: 81.85		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336646 HSP72_HUMAN (3-643): 0: 940: 77.14		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Dm
		538284 HSP7D_DROME (4-614): 0: 940: 78.89		Q9VU81_DROME (9-87): 2.81e-13: 73.9: 35.44
+	Dm
		68638 HSP7D_DROME (4-614): 0: 940: 78.89		A8JNS4_DROME (9-87): 2.9e-13: 73.9: 35.44