HitPredict

Interactor 1: HSP76 (P17066)
Heat shock 70 kDa protein 6 (Heat shock 70 kDa protein B') (Heat shock protein family A member 6)
Gene: HSPA6

Interactor 2: BAG5 (Q9UL15)
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)
Gene: BAG5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	33957083
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 643 Hs			1 447
+	Hs
		1198803 Q53FC7_HUMAN (1-643): 0: 965: 99.22		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Hs
		761536 HS71L_HUMAN (1-643): 0: 959: 79.32		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Mm
		609027 HS71B_MOUSE (5-643): 0: 937: 80.63		BAG5_MOUSE (1-447): 0: 758: 91.28
+	Mm
		989273 HSP7C_MOUSE (4-615): 0: 937: 79.25		BAG5_MOUSE (1-447): 0: 758: 91.28
+	Hs
		538096 HSP7C_HUMAN (4-615): 0: 937: 79.25		BAG5_HUMAN (1-447): 0: 752: 100.00
+	Hs
		336621 HSP76_HUMAN (1-643): 0: 970: 100.00		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347515 HSP76_HUMAN (1-643): 0: 970: 100.00		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336682 Q53FC7_HUMAN (1-643): 0: 965: 99.22		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347739 Q53FC7_HUMAN (1-643): 0: 965: 99.22		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336630 HS71L_HUMAN (1-643): 0: 959: 79.32		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347555 HS71L_HUMAN (1-643): 0: 959: 79.32		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336616 HSP7C_HUMAN (4-615): 0: 937: 79.25		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Mm
		609028 HS71B_MOUSE (5-643): 0: 937: 80.63		BAG4_MOUSE (363-441): 1.06e-29: 122: 44.30
+	Hs
		347494 HSP7C_HUMAN (4-615): 0: 937: 79.25		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Mm
		609032 HS71B_MOUSE (5-643): 0: 937: 80.63		BAG3_MOUSE (361-442): 1.13e-27: 117: 45.88
+	Mm
		989288 HSP7C_MOUSE (4-615): 0: 937: 79.25		BAG3_MOUSE (361-442): 1.13e-27: 117: 45.88
+	Hs
		347489 HS71A_HUMAN (5-643): 0: 933: 82.16		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Hs
		336646 HSP72_HUMAN (3-643): 0: 923: 77.45		BAG4_HUMAN (363-441): 3.45e-30: 123: 44.30
+	Hs
		347599 HSP72_HUMAN (3-643): 0: 923: 77.45		BAG3_HUMAN (361-442): 2.07e-28: 119: 44.71
+	Dm
		68644 HSP72_DROME (7-643): 0: 965: 71.14		A8JNS4_DROME (9-87): 2.9e-13: 73.9: 35.44