HitPredict

Interactor 1: HSP7C (P63017)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)
Gene: Hspa8

Interactor 2: BAG5 (Q8CI32)
BAG family molecular chaperone regulator 5 (BAG-5) (Bcl-2-associated athanogene 5)
Gene: BAG5

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	24510904
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	BAG~HSP70
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0048471 - perinuclear region of cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Mm			1 447
+	Mm
		609027 HS71B_MOUSE (1-646): 0: 959: 84.06		BAG5_MOUSE (1-447): 0: 774: 100.00
+	Hs
		538096 HSP7C_HUMAN (1-646): 0: 972: 99.85		BAG5_HUMAN (1-447): 0: 758: 91.28
+	Hs
		761536 HS71L_HUMAN (2-646): 0: 969: 82.64		BAG5_HUMAN (1-447): 0: 758: 91.28
+	Hs
		600958 HSP76_HUMAN (6-646): 0: 958: 77.54		BAG5_HUMAN (1-447): 0: 758: 91.28
+	Hs
		1198803 Q53FC7_HUMAN (6-646): 0: 954: 77.07		BAG5_HUMAN (1-447): 0: 758: 91.28
+	Hs
		347871 Q96IS6_HUMAN (60-646): 0: 1124: 99.83		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18
+	Hs
		336616 HSP7C_HUMAN (1-646): 0: 972: 99.85		BAG4_HUMAN (361-441): 3.2e-29: 120: 42.68
+	Hs
		336630 HS71L_HUMAN (2-646): 0: 969: 82.64		BAG4_HUMAN (361-441): 3.2e-29: 120: 42.68
+	Hs
		347494 HSP7C_HUMAN (1-646): 0: 972: 99.85		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18
+	Hs
		347555 HS71L_HUMAN (2-646): 0: 969: 82.64		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18
+	Mm
		989288 HSP7C_MOUSE (1-646): 0: 971: 100.00		BAG3_MOUSE (361-442): 4.75e-27: 115: 42.35
+	Hs
		336621 HSP76_HUMAN (6-646): 0: 958: 77.54		BAG4_HUMAN (361-441): 3.2e-29: 120: 42.68
+	Mm
		609028 HS71B_MOUSE (1-646): 0: 959: 84.06		BAG4_MOUSE (361-441): 2.5e-28: 118: 42.68
+	Hs
		347515 HSP76_HUMAN (6-646): 0: 958: 77.54		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18
+	Hs
		336682 Q53FC7_HUMAN (6-646): 0: 954: 77.07		BAG4_HUMAN (361-441): 3.2e-29: 120: 42.68
+	Mm
		609032 HS71B_MOUSE (1-646): 0: 959: 84.06		BAG3_MOUSE (361-442): 4.75e-27: 115: 42.35
+	Hs
		347739 Q53FC7_HUMAN (6-646): 0: 954: 77.07		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18
+	Hs
		347489 HS71A_HUMAN (1-646): 0: 951: 84.52		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18
+	Hs
		336646 HSP72_HUMAN (2-646): 0: 943: 85.01		BAG4_HUMAN (361-441): 3.2e-29: 120: 42.68
+	Hs
		347599 HSP72_HUMAN (2-646): 0: 943: 85.01		BAG3_HUMAN (361-442): 1.49e-27: 117: 41.18