HitPredict

Interactor 1: WDR3 (Q8BHB4)
WD repeat-containing protein 3
Gene: WDR3

Interactor 2: EED (Q921E6)
Polycomb protein EED
Gene: EED

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANAPC4_WD40~WD40
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 942 Mm			1 441
+	Hs
		268334 WDR3_HUMAN (1-942): 0: 626: 90.89		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		1288390 WDR3_HUMAN (1-942): 0: 626: 90.89		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		268049 TBL3_HUMAN (2-352): 3.4e-55: 207: 16.89		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1207948 TBL3_MOUSE (2-352): 1.46e-53: 202: 17.16		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		268105 PWP2_HUMAN (27-485): 5.52e-49: 190: 15.01		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1207284 PWP2_MOUSE (15-492): 1.4e-33: 141: 10.98		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		1240442 POC1B_HUMAN (234-563): 2.15e-57: 207: 13.22		POC1A_HUMAN (177-440): 1.72e-50: 177: 14.29
+	Hs
		1016312 TBL3_HUMAN (2-352): 3.4e-55: 207: 16.89		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		903174 TBL3_HUMAN (2-352): 3.4e-55: 207: 16.89		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		792935 LIS1_HUMAN (187-481): 7.95e-56: 200: 11.33		LIS1_HUMAN (332-438): 2.37e-14: 76.5: 18.69
+	Mm
		925836 LIS1_MOUSE (187-481): 6.41e-56: 200: 11.33		LIS1_MOUSE (332-438): 2.21e-14: 76.5: 18.69
+	Hs
		792949 LIS1_HUMAN (187-481): 7.95e-56: 200: 11.33		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Sp
		999838 TUP11_SCHPO (174-483): 2.59e-48: 184: 15.05		TUP11_SCHPO (360-440): 7.29e-14: 75.7: 18.52
+	Sp
		999842 TUP11_SCHPO (174-483): 2.59e-48: 184: 15.05		TUP12_SCHPO (332-439): 4.81e-12: 70: 14.82
+	Ca
		483033 TUP1_CANAL (184-484): 1.22e-31: 132: 12.65		TUP1_CANAL (4-179): 2.42e-26: 113: 10.38
+	Dm
		1358859 WDS_DROME (2-134): 6.79e-29: 121: 22.46		FBXW7_DROME (224-441): 2.22e-25: 111: 15.53
+	Dm
		1358845 WDS_DROME (2-134): 6.79e-29: 121: 22.46		WDS_DROME (267-440): 1.02e-23: 103: 15.34
+	Hs
		196984 WDR5_HUMAN (2-134): 1.48e-27: 116: 22.46		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51