Interactor 1: IQEC2 (Q5JU85)
IQ motif and SEC7 domain-containing protein 2
Gene: IQSEC2
Interactor 2: IQEC1 (Q6DN90)
IQ motif and SEC7 domain-containing protein 1 (ADP-ribosylation factors guanine nucleotide-exchange protein 100) (ADP-ribosylation factors guanine nucleotide-exchange protein 2) (Brefeldin-resistant Arf-GEF 2 protein) (BRAG2)
Gene: IQSEC1
Species: Homo sapiens
Source: intact
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.44 | 1.00 | 0.665 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 33961781 |
| Identification Methods | affinity chromatography technology, anti tag coimmunoprecipitation |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | IQ_SEC7_PH~Sec7, Sec7~Sec7 |
| Common GO terms | GO:0005085 - guanyl-nucleotide exchange factor activity GO:0030036 - actin cytoskeleton organization GO:0032012 - regulation of ARF protein signal transduction |
| Homologous interactions | 8 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
