HitPredict

Interactor 1: ATD3C (Q5T2N8)
ATPase family AAA domain-containing protein 3C
Gene: ATAD3C

Interactor 2: ATD3A (Q9NVI7)
ATPase family AAA domain-containing protein 3A (EC 3.6.1.-)
Gene: ATAD3A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	35575683, 38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~AAA
Common GO terms	GO:0005524 - ATP binding GO:0005739 - mitochondrion GO:0007005 - mitochondrion organization GO:0016887 - ATP hydrolysis activity
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 411 Hs			1 586
+	Dm
		1267939 ATD3A_DROME (10-401): 1.34e-149: 438: 57.14		TERA_DROME (3-585): 2.36e-139: 425: 17.03
+	Sc
		679917 PRS10_YEAST (4-391): 3.16e-103: 314: 17.28		CDC48_YEAST (3-585): 3.73e-137: 420: 16.86
+	Hs
		935189 ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95		TERA_HUMAN (3-582): 3.92e-137: 420: 15.31
+	Hs
		934388 PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16		TERA_HUMAN (3-582): 3.92e-137: 420: 15.31
+	Hs
		934402 PRS10_HUMAN (4-396): 1.75e-95: 293: 15.97		TERA_HUMAN (3-582): 3.92e-137: 420: 15.31
+	Hs
		1212142 ATD3C_HUMAN (1-411): 3.08e-105: 318: 100.00		ATD3C_HUMAN (199-586): 5.42e-122: 368: 84.06
+	Hs
		1212143 ATD3C_HUMAN (1-411): 3.08e-105: 318: 100.00		ATD3B_HUMAN (41-586): 4.07e-118: 366: 93.41
+	Hs
		1214704 ATD3B_HUMAN (3-411): 5.02e-99: 310: 80.69		ATD3B_HUMAN (41-586): 4.07e-118: 366: 93.41
+	Hs
		1214813 ATD3B_HUMAN (3-411): 5.02e-99: 310: 80.69		ATD3A_HUMAN (41-586): 7.3e-114: 353: 100.00
+	Hs
		1450570 ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95		ATD3A_HUMAN (41-586): 7.3e-114: 353: 100.00
+	Hs
		968867 PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16		PRS10_HUMAN (172-574): 1.01e-100: 312: 16.59
+	Hs
		975370 PRS10_HUMAN (4-396): 1.75e-95: 293: 15.97		PRS10_HUMAN (172-574): 1.01e-100: 312: 16.59
+	Dm
		1486181 Q9VTQ9_DROME (3-396): 6.18e-97: 297: 15.09		Q9W414_DROME (174-557): 1.69e-91: 288: 18.91
+	Sc
		921088 PRS10_YEAST (4-391): 3.16e-103: 314: 17.28		PRS10_YEAST (144-573): 6.01e-78: 255: 18.93
+	Ec
		497817 FTSH_ECOLI (12-409): 4.84e-92: 292: 15.53		FTSH_ECOLI (328-568): 1.99e-73: 248: 22.98
+	Hs
		1450617 ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95		AFG32_HUMAN (220-575): 7.27e-70: 242: 19.14
+	Hs
		1333203 ATD3A_HUMAN (3-411): 7.15e-95: 297: 79.95		AFG2A_HUMAN (2-285): 3.7e-39: 155: 11.85
+	Hs
		968994 PRS8_HUMAN (15-399): 1.18e-95: 294: 17.16		AFG2A_HUMAN (2-285): 3.7e-39: 155: 11.85