HitPredict

Interactor 1: DOCK2 (Q92608)
Dedicator of cytokinesis protein 2
Gene: DOCK2

Interactor 2: KRA94 (Q9BYQ2)
Keratin-associated protein 9-4 (Keratin-associated protein 9.4) (Ultrahigh sulfur keratin-associated protein 9.4)
Gene: KRTAP9-4

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	25416956
Identification Methods	two hybrid, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1830 Hs			1 154
+	Hs
		1267941 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KRA92_HUMAN (1-154): 1.05e-34: 120: 75.29
+	Hs
		1267940 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KRA93_HUMAN (1-154): 1.08e-33: 117: 75.61
+	Hs
		889850 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KR109_HUMAN (1-149): 4.51e-23: 93.6: 34.44
+	Hs
		889608 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KR108_HUMAN (6-154): 4.74e-22: 90.5: 29.61
+	Hs
		1216363 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KRA13_HUMAN (2-153): 3.17e-21: 85.9: 25.81
+	Hs
		888752 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KR101_HUMAN (1-149): 4e-16: 74.7: 30.92
+	Hs
		889351 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KR107_HUMAN (2-121): 8.45e-15: 72: 30.89
+	Hs
		888949 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KR103_HUMAN (27-154): 1.48e-14: 69.7: 26.36
+	Hs
		1267942 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KRA42_HUMAN (29-154): 1.06e-13: 65.8: 35.43
+	Hs
		888604 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KR123_HUMAN (44-135): 3.9e-13: 63.1: 35.79
+	Hs
		991635 DOCK2_HUMAN (1-1830): 0: 2494: 100.00		KRA11_HUMAN (41-154): 5.77e-09: 53.9: 29.58