HitPredict

Interactor 1: TERA (P55072)
Transitional endoplasmic reticulum ATPase (TER ATPase) (EC 3.6.4.6) (15S Mg(2+)-ATPase p97 subunit) (Valosin-containing protein) (VCP)
Gene: VCP

Interactor 2: ATD3A (Q9NVI7)
ATPase family AAA domain-containing protein 3A (EC 3.6.1.-)
Gene: ATAD3A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	29599191
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~AAA, AAA~AAA_lid_3, AAA~CDC48_2, AAA~CDC48_N
Common GO terms	GO:0005524 - ATP binding GO:0006974 - DNA damage response GO:0016887 - ATP hydrolysis activity
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 806 Hs			1 586
+	Rn
		857252 TERA_RAT (1-806): 0: 775: 99.88		TERA_RAT (3-582): 3.06e-137: 420: 15.31
+	Mm
		1033464 TERA_MOUSE (1-806): 0: 774: 100.00		TERA_MOUSE (3-582): 3.92e-137: 420: 15.31
+	Hs
		934326 TERA_HUMAN (1-806): 0: 774: 100.00		TERA_HUMAN (3-582): 3.92e-137: 420: 15.31
+	Dm
		1267876 TERA_DROME (5-806): 0: 760: 83.09		TERA_DROME (3-585): 2.36e-139: 425: 17.03
+	At
		930106 CD48A_ARATH (3-788): 0: 743: 77.16		CD48A_ARATH (3-585): 3.61e-141: 430: 16.67
+	Sc
		679426 CDC48_YEAST (2-806): 0: 740: 67.75		CDC48_YEAST (3-585): 3.73e-137: 420: 16.86
+	Ce
		932425 TERA1_CAEEL (3-796): 0: 727: 77.13		TERA2_CAEEL (3-581): 1.54e-138: 424: 15.96
+	Ce
		932440 TERA2_CAEEL (2-783): 0: 725: 79.03		TERA2_CAEEL (3-581): 1.54e-138: 424: 15.96
+	Ce
		932424 TERA1_CAEEL (3-796): 0: 727: 77.13		TERA1_CAEEL (3-577): 2.17e-131: 405: 16.04
+	Hs
		934402 TERA_HUMAN (1-806): 0: 774: 100.00		PRS10_HUMAN (172-574): 1.01e-100: 312: 16.59
+	Dm
		1267939 TERA_DROME (5-806): 0: 760: 83.09		ATD3A_DROME (1-584): 3.97e-101: 320: 61.86
+	Sc
		679917 CDC48_YEAST (2-806): 0: 740: 67.75		PRS10_YEAST (144-573): 6.01e-78: 255: 18.93
+	Hs
		231689 PEX1_HUMAN (9-806): 1.71e-128: 416: 23.77		TERA_HUMAN (3-582): 3.92e-137: 420: 15.31
+	Sc
		679512 CDC48_YEAST (2-806): 0: 740: 67.75		YME1_YEAST (344-553): 9.47e-12: 70.1: 30.09
+	Hs
		1333203 AFG2A_HUMAN (88-436): 5.57e-72: 255: 32.76		ATD3A_HUMAN (41-586): 7.3e-114: 353: 100.00
+	Hs
		1070439 Q0IIN5_HUMAN (184-481): 6.38e-76: 256: 34.55		Q0IIN5_HUMAN (3-293): 3.58e-40: 154: 10.85
+	Hs
		1333176 AFG2A_HUMAN (88-436): 5.57e-72: 255: 32.76		AFG2A_HUMAN (2-285): 3.7e-39: 155: 11.85
+	Sp
		153842 AFG2_SCHPO (421-801): 6.52e-71: 250: 27.48		YB7A_SCHPO (1-229): 1.12e-36: 147: 12.99
+	Hs
		1333194 AFG2A_HUMAN (88-436): 5.57e-72: 255: 32.76		AFG2B_HUMAN (2-246): 4.76e-31: 130: 10.90