HitPredict

Interactor 1: Q5U0X8 (Q5U0X8)
LD10780p
Gene: DmelCG12325

Interactor 2: Q9VFV8 (Q9VFV8)
LD47749p
Gene: DmelCG9799

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.817

Property	Details
Experiments	25242320, 22036573, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Utp12~Utp21
Common GO terms	GO:0032040 - small-subunit processome GO:0034388 - Pwp2p-containing subcomplex of 90S preribosome
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 949 Dm			1 922
+	Hs
		1144713 PWP2_HUMAN (1-908): 2.55e-169: 519: 46.32		WDR36_HUMAN (14-919): 3.59e-177: 538: 38.66
+	Sc
		678461 PWP2_YEAST (1-947): 2.19e-155: 483: 31.50		UTP21_YEAST (9-919): 3.59e-129: 413: 27.20
+	Sc
		678460 PWP2_YEAST (1-947): 2.19e-155: 483: 31.50		UTP13_YEAST (1-568): 2.26e-66: 240: 10.92
+	Hs
		1341169 WDR3_HUMAN (9-267): 4.15e-46: 181: 13.78		WDR36_HUMAN (14-919): 3.59e-177: 538: 38.66
+	Hs
		1144753 PWP2_HUMAN (1-908): 2.55e-169: 519: 46.32		WDR3_HUMAN (1-281): 9.68e-47: 183: 12.04
+	Dm
		1216729 Q5U0X8_DROME (1-949): 0: 575: 100.00		Q7JQT9_DROME (6-185): 4.96e-27: 120: 12.90
+	Dm
		1216730 Q5U0X8_DROME (1-949): 0: 575: 100.00		Q9VE98_DROME (436-730): 1.85e-22: 105: 11.22
+	Sc
		1053537 UTP12_YEAST (1-507): 2.22e-71: 257: 11.74		UTP21_YEAST (9-919): 3.59e-129: 413: 27.20
+	Hs
		1085660 PWP2_HUMAN (1-908): 2.55e-169: 519: 46.32		TBL3_HUMAN (413-847): 3.24e-32: 136: 11.07
+	Sc
		678361 PWP2_YEAST (1-947): 2.19e-155: 483: 31.50		PWP2_YEAST (5-312): 9.94e-29: 126: 11.42
+	Sc
		678486 PWP2_YEAST (1-947): 2.19e-155: 483: 31.50		UTP12_YEAST (11-111): 2.96e-10: 66.5: 10.58
+	Sc
		1053135 UTP12_YEAST (1-507): 2.22e-71: 257: 11.74		UTP13_YEAST (1-568): 2.26e-66: 240: 10.92
+	Bt
		773429 COPB2_BOVIN (4-335): 5.58e-52: 199: 12.97		COPA_BOVIN (11-566): 3.3e-56: 213: 11.96
+	Hs
		773461 COPB2_HUMAN (4-335): 9.28e-52: 198: 12.97		COPA_HUMAN (11-566): 4.21e-55: 210: 12.13
+	Hs
		773471 COPB2_HUMAN (4-335): 9.28e-52: 198: 12.97		WDR5_HUMAN (427-700): 3.81e-47: 173: 12.72
+	Hs
		921858 WDR5_HUMAN (598-860): 1.43e-39: 151: 8.71		COPA_HUMAN (11-566): 4.21e-55: 210: 12.13
+	Dm
		1463899 WDS_DROME (554-866): 6.26e-54: 193: 13.97		WDS_DROME (14-234): 4.94e-37: 145: 16.81
+	Hs
		964797 WDR5_HUMAN (598-860): 1.43e-39: 151: 8.71		WDR5_HUMAN (427-700): 3.81e-47: 173: 12.72
+	Hs
		1085730 WDR3_HUMAN (9-267): 4.15e-46: 181: 13.78		TBL3_HUMAN (413-847): 3.24e-32: 136: 11.07