HitPredict

Interactor 1: Q5U0Y0 (Q5U0Y0)
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)
Gene: Sin3A

Interactor 2: Q9VWP5 (Q9VWP5)
Hat-trick, isoform D
Gene: htk

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	20566628, 38944040
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003682 - chromatin binding GO:0005634 - nucleus GO:0070822 - Sin3-type complex
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 2062 Dm			1 2486
+	Dm
		1216745 Q5U0Y0_DROME (1-2062): 0: 1903: 100.00		KDM5_DROME (146-470): 6.21e-58: 225: 16.49
+	Dm
		52088 Q5U0Y0_DROME (1-2062): 0: 1903: 100.00		A1Z6M0_DROME (257-383): 2.92e-12: 74.9: 21.97
+	Hs
		1195588 SIN3A_HUMAN (172-680): 4.58e-51: 201: 20.85		ARI4B_HUMAN (1-520): 6.75e-144: 487: 35.57
+	Hs
		711787 SIN3A_HUMAN (172-680): 4.58e-51: 201: 20.85		ARI4A_HUMAN (1-448): 1.16e-126: 435: 37.11
+	Hs
		274338 SIN3B_HUMAN (260-700): 5.34e-35: 148: 17.65		ARI4B_HUMAN (1-520): 6.75e-144: 487: 35.57
+	Hs
		274284 SIN3B_HUMAN (260-700): 5.34e-35: 148: 17.65		ARI4A_HUMAN (1-448): 1.16e-126: 435: 37.11
+	Mm
		60008 SIN3A_MOUSE (172-680): 4.78e-52: 204: 20.66		ARI1A_MOUSE (281-629): 8.2e-52: 205: 15.97
+	Mm
		1221128 SIN3A_MOUSE (172-680): 4.78e-52: 204: 20.66		KDM5B_MOUSE (239-515): 1.56e-49: 197: 17.91
+	Hs
		274285 SIN3B_HUMAN (260-700): 5.34e-35: 148: 17.65		KDM5A_HUMAN (238-471): 2.11e-47: 190: 16.67
+	Hs
		154693 MDC1_HUMAN (15-582): 2.73e-19: 97.9: 8.45		ARI1A_HUMAN (281-629): 1.71e-52: 207: 15.97
+	Hs
		1129659 MDC1_HUMAN (15-582): 2.73e-19: 97.9: 8.45		ARI1B_HUMAN (228-610): 2.92e-52: 206: 15.07