HitPredict

Interactor 1: PSD12 (O00232)
26S proteasome non-ATPase regulatory subunit 12 (26S proteasome regulatory subunit RPN5) (26S proteasome regulatory subunit p55)
Gene: PSMD12

Interactor 2: PSMD6 (Q15008)
26S proteasome non-ATPase regulatory subunit 6 (26S proteasome regulatory subunit RPN7) (26S proteasome regulatory subunit S10) (Breast cancer-associated protein SGA-113M) (Phosphonoformate immuno-associated protein 4) (Proteasome regulatory particle subunit p44S10) (p42A)
Gene: PSMD6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.82 1.00 0.906

The method score is based on:

Property Details
Experiments 28514442, 33961781, 35271311, 17353931
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains PCI~PCI, PCI~RPN7
Common GO terms GO:0000502 - proteasome complex
GO:0005576 - extracellular region
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0005838 - proteasome regulatory particle
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 456
Hs

1 389
+ Dm
+ Hs
+ Hs
+ Mm
+ Dm
+ Mm
+ Hs
+ Sc
+ Mm
+ Hs
+ At
+ Hs
+ Hs
+ Zm
+ An
+ An
+ Hs
+ Hs
+ Dm
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024