HitPredict

Interactor 1: DVL2 (Q60838)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: VANG1 (Q80Z96)
Vang-like protein 1 (Loop-tail protein 2) (Van Gogh-like protein 1)
Gene: Vangl1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.49	0.60	0.543

Property	Details
Experiments	15456783
Identification Methods	affinity chromatography technology, two hybrid, pull down, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016328 - lateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 736 Mm			1 526
+	Hs
		159758 DVL2_HUMAN (1-736): 4.81e-180: 534: 96.60		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Mm
		900716 DVL1_MOUSE (11-736): 1.7e-158: 477: 58.27		VANG1_MOUSE (1-526): 0: 816: 100.00
+	Mm
		1222229 DVL3_MOUSE (11-736): 8.85e-153: 463: 64.63		VANG1_MOUSE (1-526): 0: 816: 100.00
+	Hs
		1346608 DVL3_HUMAN (11-736): 4.55e-153: 463: 64.50		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Mm
		1221613 DVL2_MOUSE (13-736): 0: 540: 100.00		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Hs
		159915 DVL2_HUMAN (1-736): 4.81e-180: 534: 96.60		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Mm
		900720 DVL1_MOUSE (11-736): 1.7e-158: 477: 58.27		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Mm
		1222233 DVL3_MOUSE (11-736): 8.85e-153: 463: 64.63		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Hs
		1371474 DVL3_HUMAN (11-736): 4.55e-153: 463: 64.50		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Dm
		233678 DSH_DROME (6-563): 5.68e-117: 367: 46.05		O45030_DROME (21-526): 0: 679: 44.85
+	Dm
		53367 DSH_DROME (6-563): 5.68e-117: 367: 46.05		A1Z7N9_DROME (21-526): 0: 679: 44.85
+	Mm
		1223603 DLG4_MOUSE (117-534): 5.84e-48: 183: 17.02		VANG1_MOUSE (1-526): 0: 816: 100.00
+	Hs
		1091542 DLG1_HUMAN (95-708): 2.88e-46: 179: 15.96		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Hs
		936391 AFAD_HUMAN (262-701): 1.23e-43: 172: 19.44		VANG1_HUMAN (1-526): 0: 801: 95.06
+	Ce
		115049 Q18239_CAEEL (14-644): 2.55e-85: 287: 28.53		H2KY90_CAEEL (49-526): 0: 664: 34.72
+	Hs
		1288944 RIMS1_HUMAN (85-722): 3.92e-50: 192: 13.83		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Mm
		1223692 DLG4_MOUSE (117-534): 5.84e-48: 183: 17.02		VANG2_MOUSE (1-526): 0: 662: 71.02
+	Rn
		723870 DLG4_RAT (117-534): 1.41e-47: 181: 16.55		VANG2_RAT (1-526): 0: 662: 71.02
+	Hs
		1091596 DLG1_HUMAN (95-708): 2.88e-46: 179: 15.96		VANG2_HUMAN (1-526): 0: 658: 71.21
+	Hs
		936483 AFAD_HUMAN (262-701): 1.23e-43: 172: 19.44		VANG2_HUMAN (1-526): 0: 658: 71.21