Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: VANG2 (Q9ULK5)
Vang-like protein 2 (Loop-tail protein 1 homolog) (Strabismus 1) (Van Gogh-like protein 2)
Gene: VANGL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.70 0.60 0.650

The method score is based on:

Property Details
Experiments 33961781, 36398662, unassigned3799
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001843 - neural tube closure
GO:0001947 - heart looping
GO:0016328 - lateral plasma membrane
GO:0022007 - convergent extension involved in neural plate elongation
GO:0032956 - regulation of actin cytoskeleton organization
and 2 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 736
Hs

1 521
+ Hs
+ Mm
+ Mm
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Mm
+ Hs
+ Dm
+ Dm
+ Mm
+ Hs
+ Mm
+ Rn
+ Hs
+ Ce
+ Dm
+ Dm

Service provided by Combinatics, Japan

Last updated: 11Aug2025