HitPredict

Interactor 1: DVL3 (Q61062)
Segment polarity protein dishevelled homolog DVL-3 (Dishevelled-3) (DSH homolog 3)
Gene: DVL3

Interactor 2: VANG2 (Q91ZD4)
Vang-like protein 2 (Loop-tail protein 1) (Loop-tail-associated protein) (Van Gogh-like protein 2)
Gene: Vangl2

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.529

Property	Details
Experiments	15456783
Identification Methods	affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003148 - outflow tract septum morphogenesis GO:0035567 - non-canonical Wnt signaling pathway GO:0060071 - Wnt signaling pathway, planar cell polarity pathway GO:0090103 - cochlea morphogenesis GO:0098978 - glutamatergic synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 716 Mm			1 521
+	Hs
		1346608 DVL3_HUMAN (1-716): 6.2e-160: 480: 99.02		VANG1_HUMAN (21-521): 0: 777: 72.48
+	Mm
		1222229 DVL3_MOUSE (1-716): 8.94e-160: 480: 100.00		VANG1_MOUSE (21-521): 0: 763: 71.20
+	Hs
		1371474 DVL3_HUMAN (1-716): 6.2e-160: 480: 99.02		VANG2_HUMAN (1-521): 0: 723: 99.42
+	Mm
		900716 DVL1_MOUSE (1-716): 2.66e-143: 437: 62.69		VANG1_MOUSE (21-521): 0: 763: 71.20
+	Mm
		900720 DVL1_MOUSE (1-716): 2.66e-143: 437: 62.69		VANG2_MOUSE (1-521): 0: 724: 100.00
+	Hs
		159758 DVL2_HUMAN (3-716): 3.12e-120: 378: 64.90		VANG1_HUMAN (21-521): 0: 777: 72.48
+	Mm
		1221606 DVL2_MOUSE (3-716): 1.7e-124: 389: 63.77		VANG1_MOUSE (21-521): 0: 763: 71.20
+	Mm
		1221613 DVL2_MOUSE (3-716): 1.7e-124: 389: 63.77		VANG2_MOUSE (1-521): 0: 724: 100.00
+	Hs
		159915 DVL2_HUMAN (3-716): 3.12e-120: 378: 64.90		VANG2_HUMAN (1-521): 0: 723: 99.42
+	Hs
		1091542 DLG1_HUMAN (22-656): 1.97e-53: 200: 13.84		VANG1_HUMAN (21-521): 0: 777: 72.48
+	Dm
		233678 DSH_DROME (3-559): 5.82e-91: 298: 46.40		O45030_DROME (16-521): 0: 676: 43.91
+	Dm
		53367 DSH_DROME (3-559): 5.82e-91: 298: 46.40		A1Z7N9_DROME (16-521): 0: 676: 43.91
+	Mm
		1223603 DLG4_MOUSE (93-627): 1.38e-51: 193: 13.92		VANG1_MOUSE (21-521): 0: 763: 71.20
+	Hs
		1346602 PARD3_HUMAN (84-645): 2.18e-41: 164: 15.01		VANG1_HUMAN (21-521): 0: 777: 72.48
+	Ce
		115049 Q18239_CAEEL (4-625): 2.71e-83: 281: 30.24		H2KY90_CAEEL (2-521): 0: 651: 30.24
+	Hs
		1091596 DLG1_HUMAN (22-656): 1.97e-53: 200: 13.84		VANG2_HUMAN (1-521): 0: 723: 99.42
+	Mm
		1223692 DLG4_MOUSE (93-627): 1.38e-51: 193: 13.92		VANG2_MOUSE (1-521): 0: 724: 100.00
+	Rn
		723870 DLG4_RAT (93-627): 4.83e-51: 191: 13.56		VANG2_RAT (1-521): 0: 724: 100.00
+	Dm
		233677 DLG1_DROME (1-644): 1.48e-47: 183: 13.45		O45030_DROME (16-521): 0: 676: 43.91
+	Dm
		53366 DLG1_DROME (1-644): 1.48e-47: 183: 13.45		A1Z7N9_DROME (16-521): 0: 676: 43.91