HitPredict

Interactor 1: LASP1 (Q61792)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Interactor 2: ZYX (Q62523)
Zyxin
Gene: ZYX

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.647

Property	Details
Experiments	15465019
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005925 - focal adhesion GO:0046872 - metal ion binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 263 Mm			1 564
+	Hs
		1133088 LASP1_HUMAN (1-263): 2.71e-57: 185: 94.68		ZYX_HUMAN (1-564): 8.81e-68: 231: 85.19
+	Hs
		302173 NEBL_HUMAN (94-263): 1.44e-23: 101: 37.43		ZYX_HUMAN (1-564): 8.81e-68: 231: 85.19
+	Hs
		1156196 SRBS1_HUMAN (145-263): 5.62e-19: 88: 21.85		ZYX_HUMAN (1-564): 8.81e-68: 231: 85.19
+	Hs
		1154088 ITSN1_HUMAN (33-263): 5.95e-14: 73.4: 14.29		ZYX_HUMAN (1-564): 8.81e-68: 231: 85.19
+	Hs
		1156126 SH3R1_HUMAN (178-263): 2.97e-13: 71.2: 24.42		ZYX_HUMAN (1-564): 8.81e-68: 231: 85.19
+	Hs
		878457 SRC8_HUMAN (42-262): 1.21e-24: 104: 21.89		PAXI_HUMAN (8-562): 3.83e-53: 192: 15.83
+	Hs
		1154154 ITSN1_HUMAN (33-263): 5.95e-14: 73.4: 14.29		AJUBA_HUMAN (38-562): 1.14e-63: 219: 24.15
+	Hs
		1133189 LASP1_HUMAN (1-263): 2.71e-57: 185: 94.68		TES_HUMAN (429-563): 2.02e-24: 107: 21.99
+	Hs
		878581 ASAP1_HUMAN (36-263): 3.35e-23: 100: 13.10		PAXI_HUMAN (8-562): 3.83e-53: 192: 15.83
+	Hs
		878550 SRBS1_HUMAN (145-263): 5.62e-19: 88: 21.85		PAXI_HUMAN (8-562): 3.83e-53: 192: 15.83
+	Mm
		1223339 LASP1_MOUSE (1-263): 3.42e-60: 193: 100.00		LPP_MOUSE (4-487): 1.01e-15: 82.4: 15.52
+	Hs
		878496 SH3R1_HUMAN (178-263): 2.97e-13: 71.2: 24.42		PAXI_HUMAN (8-562): 3.83e-53: 192: 15.83
+	Hs
		1133138 LASP1_HUMAN (1-263): 2.71e-57: 185: 94.68		LPP_HUMAN (4-487): 3.07e-13: 74.3: 14.68
+	Hs
		1116475 LASP1_HUMAN (1-263): 2.71e-57: 185: 94.68		FHL3_HUMAN (402-536): 3.7e-09: 60.1: 28.99
+	Hs
		1459527 DBNL_HUMAN (75-263): 9.3e-34: 128: 24.23		TES_HUMAN (429-563): 2.02e-24: 107: 21.99
+	Hs
		1124750 SRC8_HUMAN (42-262): 1.21e-24: 104: 21.89		TES_HUMAN (429-563): 2.02e-24: 107: 21.99
+	Hs
		635500 NEBU_HUMAN (15-263): 4.17e-24: 103: 27.30		LIMS1_HUMAN (390-536): 6.57e-09: 59.7: 26.80
+	Hs
		302168 NEBL_HUMAN (94-263): 1.44e-23: 101: 37.43		FHL3_HUMAN (402-536): 3.7e-09: 60.1: 28.99
+	Hs
		1123021 SH3R1_HUMAN (178-263): 2.97e-13: 71.2: 24.42		FHL2_HUMAN (460-564): 4.45e-19: 89.6: 23.81
+	Hs
		1116503 CRIP3_HUMAN (5-54): 5.33e-15: 73.8: 38.00		FHL3_HUMAN (402-536): 3.7e-09: 60.1: 28.99