Protein: ITA2
Integrin alpha-2 (CD49 antigen-like family member B) (Collagen receptor) (Platelet membrane glycoprotein Ia) (GPIa) (VLA-2 subunit alpha) (CD antigen CD49b)

Gene: ITA2, ITGA2
Organism: Homo sapiens
Interactions: 97
UniProt ID: P17301

Gene Ontology (top 5):
GO:0001540 - amyloid-beta binding
GO:0001618 - virus receptor activity
GO:0001666 - response to hypoxia
GO:0002687 - positive regulation of leukocyte migration
GO:0005178 - integrin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

403772

ITB1
Integrin beta-1

4

20

Small-scale

0.883

High

566889

BTNL8
Butyrophilin-like protein 8

3

11

High-throughput

0.861

High

566852

PRTN3
Myeloblastin

1

13

High-throughput

0.691

High

566884

CL12B
C-type lectin domain family 12 member B

1

4

High-throughput

0.691

High

566909

BTNL2
Butyrophilin-like protein 2

1

12

High-throughput

0.691

High

121102

LEG8
Galectin-8

3

20

High-throughput

0.667

High

566849

LEG3
Galectin-3

3

20

High-throughput

0.667

High

566886

ZACN
Ligand-gated cation channel ZACN

3

1

High-throughput

0.667

High

566891

SPA12
Serpin A12

2

5

High-throughput

0.628

High

548825

MCP
Membrane cofactor protein

1

5

Small-scale

0.618

High

566907

MGT4C
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase C

2

0

High-throughput

0.602

High

566901

SHRPN
Sharpin

1

7

Small-scale

0.597

High

566848

ITA2
Integrin alpha-2

1

9

Small-scale

0.590

High

349856

RASK
GTPase KRas

2

20

High-throughput

0.584

High

506870

LAMP1
Lysosome-associated membrane glycoprotein 1

2

5

High-throughput

0.584

High

566871

RB11A
Ras-related protein Rab-11A

2

4

High-throughput

0.584

High

566872

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.584

High

328103

SG1D1
Secretoglobin family 1D member 1

2

3

High-throughput

0.574

High

566894

TMED6
Transmembrane emp24 domain-containing protein 6

2

2

High-throughput

0.574

High

566850

RAB5A
Ras-related protein Rab-5A

2

6

High-throughput

0.571

High

566855

PDIA3
Protein disulfide-isomerase A3

1

7

Small-scale

0.561

High

261075

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

372727

MMP1
Interstitial collagenase

2

11

Small-scale

0.543

High

61674

CDHR4
Cadherin-related family member 4

1

9

High-throughput

0.536

High

328251

BY55
CD160 antigen

1

4

High-throughput

0.536

High

449180

LEG1
Galectin-1

1

20

High-throughput

0.536

High

474692

CFC1
Cryptic protein

1

1

High-throughput

0.536

High

528492

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.536

High

547686

ATF2
Cyclic AMP-dependent transcription factor ATF-2

1

5

High-throughput

0.536

High

566896

ASIC4
Acid-sensing ion channel 4

1

2

High-throughput

0.536

High

566904

PICK1
PRKCA-binding protein

1

4

High-throughput

0.536

High

566910

FBX2
F-box only protein 2

1

14

High-throughput

0.536

High

566883

CAH9
Carbonic anhydrase 9

1

6

High-throughput

0.515

High

394073

A4
Amyloid-beta precursor protein

1

6

Small-scale

0.501

High

436008

CO1A2
Collagen alpha-2(I) chain

1

9

Small-scale

0.501

High

566853

LAMA1
Laminin subunit alpha-1

1

3

Small-scale

0.501

High

363713

ALBU
Albumin

1

1

High-throughput

0.489

High

514338

PSPC
Surfactant protein C

1

5

High-throughput

0.489

High

566861

DNSL1
Deoxyribonuclease-1-like 1

1

1

High-throughput

0.489

High

566863

EP3B
Epididymal secretory protein E3-beta

1

5

High-throughput

0.489

High

566876

NAAA
N-acylethanolamine-hydrolyzing acid amidase

1

3

High-throughput

0.489

High

566882

TAZ
Tafazzin

1

3

High-throughput

0.489

High

566888

BRID5
BRICHOS domain-containing protein 5

1

4

High-throughput

0.489

High

566895

CA054
Uncharacterized protein C1orf54

1

4

High-throughput

0.489

High

566897

LCFC1
Sperm-egg fusion protein LLCFC1

1

4

High-throughput

0.489

High

566905

CBLN4
Cerebellin-4

1

20

High-throughput

0.489

High

566851

CD9
CD9 antigen

1

20

High-throughput

0.484

High

120298

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.479

High

126911

WASL
Actin nucleation-promoting factor WASL

1

5

Small-scale

0.479

High

205013

TGON2
Trans-Golgi network integral membrane protein 2

1

11

High-throughput

0.479

High

318057

DIRA3
GTP-binding protein Di-Ras3

1

8

High-throughput

0.479

High

337892

EGFR
Epidermal growth factor receptor

1

11

Small-scale

0.479

High

349109

RASH
GTPase HRas

1

13

High-throughput

0.479

High

433566

LYN
Tyrosine-protein kinase Lyn

1

6

High-throughput

0.479

High

564407

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.479

High

566854

MARCS
Myristoylated alanine-rich C-kinase substrate

1

2

High-throughput

0.479

High

566856

UFO
Tyrosine-protein kinase receptor UFO

1

9

Small-scale

0.479

High

566857

CTNB1
Catenin beta-1

1

5

Small-scale

0.479

High

566858

VGFR2
Vascular endothelial growth factor receptor 2

1

6

Small-scale

0.479

High

566859

VHL
von Hippel-Lindau disease tumor suppressor

1

3

Small-scale

0.479

High

566864

RAB25
Ras-related protein Rab-25

1

4

High-throughput

0.479

High

566865

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.479

High

566867

RHOA
Transforming protein RhoA

1

20

High-throughput

0.479

High

566868

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.479

High

566870

ARF6
ADP-ribosylation factor 6

1

7

High-throughput

0.479

High

566873

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.479

High

566875

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.479

High

566877

CAV1
Caveolin-1

1

4

High-throughput

0.479

High

566879

CD166
CD166 antigen

1

4

Small-scale

0.479

High

566880

FHL2
Four and a half LIM domains protein 2

1

10

Small-scale

0.479

High

566881

RAB35
Ras-related protein Rab-35

1

7

High-throughput

0.479

High

566892

CXD3
Gap junction delta-3 protein

1

3

High-throughput

0.479

High

566898

CIB1
Calcium and integrin-binding protein 1

1

2

Small-scale

0.479

High

566900

ACE2
Angiotensin-converting enzyme 2

1

1

Small-scale

0.479

High

566903

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.479

High

566908

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

566911

LAMP3
Lysosome-associated membrane glycoprotein 3

1

5

High-throughput

0.479

High

566887

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

402690

FABPH
Fatty acid-binding protein, heart

1

1

Small-scale

0.457

High

326020

TSN15
Tetraspanin-15

1

20

High-throughput

0.445

High

358468

CO1A1
Collagen alpha-1(I) chain

1

8

Small-scale

0.445

High

566869

TSN5
Tetraspanin-5

1

20

High-throughput

0.445

High

566893

TSN14
Tetraspanin-14

1

20

High-throughput

0.445

High

256799

T22D2
TSC22 domain family protein 2

1

4

Small-scale

0.439

High

566860

MSS4
Guanine nucleotide exchange factor MSS4

1

3

Small-scale

0.439

High

566912

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

5

Small-scale

0.439

High

559318

H13
Histone H1.3

1

4

High-throughput

0.437

High

566866

RAB2A
Ras-related protein Rab-2A

1

6

High-throughput

0.437

High

566874

RNF4
E3 ubiquitin-protein ligase RNF4

1

4

High-throughput

0.437

High

566890

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

566906

OTULL
Inactive ubiquitin thioesterase OTULINL

1

3

High-throughput

0.437

High

566878

CD47
Leukocyte surface antigen CD47

1

0

Small-scale

0.426

High

566885

DB109
Putative beta-defensin 109B

1

3

High-throughput

0.407

High

566899

RSRP1
Arginine/serine-rich protein 1

1

0

High-throughput

0.279

Low

566902

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.279

Low

566862

PSMD4
26S proteasome non-ATPase regulatory subunit 4

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024