Protein: NEBL
Nebulette (Actin-binding Z-disk protein)

Gene: NEBL
Organism: Homo sapiens
Interactions: 88
UniProt ID: O76041

Gene Ontology (top 5):
GO:0001725 - stress fiber
GO:0005523 - tropomyosin binding
GO:0008092 - cytoskeletal protein binding
GO:0008307 - structural constituent of muscle
GO:0030018 - Z disc

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

302170

ACAP1
Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

2

18

High-throughput

0.700

High

302173

ZYX
Zyxin

3

13

Small-scale

0.650

High

302165

TRAF2
TNF receptor-associated factor 2

4

13

High-throughput

0.637

High

302214

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

4

13

High-throughput

0.637

High

302187

ZDH17
Palmitoyltransferase ZDHHC17

1

16

High-throughput

0.625

High

62744

XIRP2
Xin actin-binding repeat-containing protein 2

1

3

Small-scale

0.607

High

302143

VINC
Vinculin

2

11

High-throughput

0.606

High

302205

KIFC3
Kinesin-like protein KIFC3

2

9

High-throughput

0.606

High

302179

XIRP1
Xin actin-binding repeat-containing protein 1

1

3

Small-scale

0.598

High

302198

ZN764
Zinc finger protein 764

2

7

High-throughput

0.574

High

302164

GOGA2
Golgin subfamily A member 2

2

17

High-throughput

0.573

High

302166

TRAF1
TNF receptor-associated factor 1

2

8

High-throughput

0.573

High

302200

CC136
Coiled-coil domain-containing protein 136

2

18

High-throughput

0.566

High

302153

SYQ
Glutamine--tRNA ligase

2

1

High-throughput

0.553

High

302194

P55G
Phosphatidylinositol 3-kinase regulatory subunit gamma

2

20

High-throughput

0.553

High

302202

SPAG5
Sperm-associated antigen 5

2

20

High-throughput

0.553

High

302211

GOG6A
Golgin subfamily A member 6A

2

20

High-throughput

0.553

High

302162

ZO1
Tight junction protein 1

1

16

High-throughput

0.553

High

302212

ZO2
Tight junction protein 2

1

16

High-throughput

0.553

High

302213

UBQL2
Ubiquilin-2

1

13

High-throughput

0.553

High

302168

FHL3
Four and a half LIM domains protein 3

1

10

High-throughput

0.536

High

302140

TRI27
Zinc finger protein RFP

1

8

High-throughput

0.523

High

302185

NUTM1
NUT family member 1

1

2

High-throughput

0.523

High

302204

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.523

High

302210

HOME3
Homer protein homolog 3

1

20

High-throughput

0.523

High

302133

ESR1
Estrogen receptor

2

20

High-throughput

0.521

High

302196

ESR2
Estrogen receptor beta

2

20

High-throughput

0.521

High

302134

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

1

High-throughput

0.515

High

302135

A4
Amyloid-beta precursor protein

1

5

High-throughput

0.515

High

302156

DYN2
Dynamin-2

1

20

High-throughput

0.515

High

302197

TRI63
E3 ubiquitin-protein ligase TRIM63

1

20

High-throughput

0.508

High

225508

AAKB2
5'-AMP-activated protein kinase subunit beta-2

1

3

High-throughput

0.494

High

302190

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

1

High-throughput

0.494

High

302207

TMG4
Transmembrane gamma-carboxyglutamic acid protein 4

1

1

Small-scale

0.489

High

302137

TAU
Microtubule-associated protein tau

1

20

High-throughput

0.489

High

302151

KDM5C
Lysine-specific demethylase 5C

1

3

High-throughput

0.489

High

302172

PCM1
Pericentriolar material 1 protein

1

1

High-throughput

0.489

High

302195

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16

1

1

High-throughput

0.489

High

302163

ACTN3
Alpha-actinin-3

1

18

High-throughput

0.481

High

302183

MYPN
Myopalladin

1

8

Small-scale

0.481

High

302138

CADH1
Cadherin-1

1

8

High-throughput

0.479

High

302141

EZRI
Ezrin

1

20

High-throughput

0.479

High

302144

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

3

High-throughput

0.479

High

302148

CTNA1
Catenin alpha-1

1

10

High-throughput

0.479

High

302150

RADI
Radixin

1

20

High-throughput

0.479

High

302155

VASP
Vasodilator-stimulated phosphoprotein

1

18

High-throughput

0.479

High

302158

H2B1D
Histone H2B type 1-D

1

20

High-throughput

0.479

High

302159

ACTB
Actin, cytoplasmic 1

1

20

High-throughput

0.479

High

302160

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

2

High-throughput

0.479

High

302167

CUL3
Cullin-3

1

8

High-throughput

0.479

High

302203

H2B1L
Histone H2B type 1-L

1

20

High-throughput

0.479

High

73650

B2R8Y4
cDNA, FLJ94117, highly similar to Homo sapiens actinin, alpha 3

1

18

High-throughput

0.470

High

245836

KIF1B
Kinesin-like protein KIF1B

1

16

High-throughput

0.470

High

302132

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

20

High-throughput

0.470

High

302136

NFL
Neurofilament light polypeptide

1

20

High-throughput

0.470

High

302139

GFAP
Glial fibrillary acidic protein

1

20

High-throughput

0.470

High

302149

MERL
Merlin

1

20

High-throughput

0.470

High

302152

HD
Huntingtin

1

12

High-throughput

0.470

High

302154

PSN2
Presenilin-2

1

1

High-throughput

0.470

High

302157

ATX1
Ataxin-1

1

3

High-throughput

0.470

High

302174

Q4G0R1
PIBF1 protein

1

3

High-throughput

0.470

High

302175

GLE1
mRNA export factor GLE1

1

16

High-throughput

0.470

High

302176

Q53SE7
Germ cell-less homolog 1

1

4

High-throughput

0.470

High

302182

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

17

High-throughput

0.470

High

302193

PIBF1
Progesterone-induced-blocking factor 1

1

3

High-throughput

0.439

High

302199

GMCL1
Germ cell-less protein-like 1

1

4

High-throughput

0.439

High

302206

TRI55
Tripartite motif-containing protein 55

1

20

High-throughput

0.439

High

302131

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.437

High

302147

PUR8
Adenylosuccinate lyase

1

1

High-throughput

0.437

High

302161

CXAR
Coxsackievirus and adenovirus receptor

1

3

High-throughput

0.437

High

302169

DCTN1
Dynactin subunit 1

1

11

High-throughput

0.437

High

302171

KIF14
Kinesin-like protein KIF14

1

18

High-throughput

0.437

High

302177

CE170
Centrosomal protein of 170 kDa

1

12

High-throughput

0.437

High

302178

CE128
Centrosomal protein of 128 kDa

1

16

High-throughput

0.437

High

302184

NAA40
N-alpha-acetyltransferase 40

1

5

High-throughput

0.437

High

302201

SCLT1
Sodium channel and clathrin linker 1

1

20

High-throughput

0.437

High

302209

SMUF2
E3 ubiquitin-protein ligase SMURF2

1

14

High-throughput

0.417

High

302146

GFRP
GTP cyclohydrolase 1 feedback regulatory protein

2

0

High-throughput

0.328

High

302186

CC125
Coiled-coil domain-containing protein 125

2

0

High-throughput

0.316

High

302191

CEP70
Centrosomal protein of 70 kDa

2

0

High-throughput

0.316

High

302189

FAM9B
Protein FAM9B

1

0

High-throughput

0.299

High

302192

MIPO1
Mirror-image polydactyly gene 1 protein

1

0

High-throughput

0.299

High

302145

G0S2
G0/G1 switch protein 2

1

0

High-throughput

0.279

Low

302181

TAFA5
Chemokine-like protein TAFA-5

1

0

High-throughput

0.279

Low

302188

NNRD
ATP-dependent

1

0

High-throughput

0.279

Low

302208

MED28
Mediator of RNA polymerase II transcription subunit 28

1

0

Small-scale

0.269

Low

302180

PEX26
Peroxisome assembly protein 26

1

0

High-throughput

0.268

Low

302142

PYRG1
CTP synthase 1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025