HitPredict

Interactor 1: LASP1 (Q14847)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Interactor 2: LPP (Q93052)
Lipoma-preferred partner (LIM domain-containing preferred translocation partner in lipoma)
Gene: LPP

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	22665060
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	LIM~LIM
Common GO terms	GO:0005925 - focal adhesion GO:0046872 - metal ion binding
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 261 Hs			1 612
+	Hs
		1133088 LASP1_HUMAN (1-261): 6.65e-59: 189: 100.00		ZYX_HUMAN (112-602): 2.6e-101: 321: 36.03
+	Mm
		1223334 LASP1_MOUSE (1-261): 1.03e-56: 184: 95.06		ZYX_MOUSE (107-602): 9.06e-103: 324: 34.00
+	Mm
		1223339 LASP1_MOUSE (1-261): 1.03e-56: 184: 95.06		LPP_MOUSE (1-612): 1.68e-86: 283: 89.07
+	Hs
		302173 NEBL_HUMAN (36-261): 6.7e-29: 117: 31.67		ZYX_HUMAN (112-602): 2.6e-101: 321: 36.03
+	Hs
		1121952 ARHG7_HUMAN (43-261): 1.27e-25: 107: 14.16		ZYX_HUMAN (112-602): 2.6e-101: 321: 36.03
+	Hs
		1156108 SH319_HUMAN (189-261): 2.13e-13: 71.4: 35.62		ZYX_HUMAN (112-602): 2.6e-101: 321: 36.03
+	Hs
		1156196 SRBS1_HUMAN (149-259): 7.57e-13: 69.9: 31.30		ZYX_HUMAN (112-602): 2.6e-101: 321: 36.03
+	Hs
		878455 ARHG7_HUMAN (43-261): 1.27e-25: 107: 14.16		PAXI_HUMAN (2-601): 3.09e-54: 196: 15.85
+	Hs
		878457 SRC8_HUMAN (38-260): 1.53e-23: 101: 17.62		PAXI_HUMAN (2-601): 3.09e-54: 196: 15.85
+	Hs
		878550 SRBS1_HUMAN (149-259): 7.57e-13: 69.9: 31.30		PAXI_HUMAN (2-601): 3.09e-54: 196: 15.85
+	Hs
		1116475 LASP1_HUMAN (1-261): 6.65e-59: 189: 100.00		FHL3_HUMAN (440-572): 8.44e-12: 68.2: 32.35
+	Hs
		1133189 LASP1_HUMAN (1-261): 6.65e-59: 189: 100.00		TES_HUMAN (529-612): 8.29e-09: 60: 17.86
+	Mm
		266989 PLCG2_MOUSE (17-261): 7.24e-22: 96.5: 13.88		FHL2_MOUSE (442-610): 4.73e-38: 143: 22.47
+	Hs
		302168 NEBL_HUMAN (36-261): 6.7e-29: 117: 31.67		FHL3_HUMAN (440-572): 8.44e-12: 68.2: 32.35
+	Hs
		253950 ARHG7_HUMAN (43-261): 1.27e-25: 107: 14.16		LPXN_HUMAN (355-474): 8e-10: 63.1: 17.50
+	Hs
		1459527 DBNL_HUMAN (59-261): 1.64e-25: 106: 23.65		TES_HUMAN (529-612): 8.29e-09: 60: 17.86
+	Hs
		1124750 SRC8_HUMAN (38-260): 1.53e-23: 101: 17.62		TES_HUMAN (529-612): 8.29e-09: 60: 17.86
+	Hs
		1116503 CRIP3_HUMAN (5-55): 7.1e-15: 73.4: 37.26		FHL3_HUMAN (440-572): 8.44e-12: 68.2: 32.35