Interactor 1: SIN3B (Q62141)
Paired amphipathic helix protein Sin3b (Histone deacetylase complex subunit Sin3b) (Transcriptional corepressor Sin3b)
Gene: SIN3B

Interactor 2: SDS3 (Q8BR65)
Sin3 histone deacetylase corepressor complex component SDS3 (Suppressor of defective silencing 3 protein homolog)
Gene: Suds3

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.63 1.00 0.796

The method score is based on:

Property Details
Experiments 15489224, 11909966
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, two hybrid, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains PAH~Sds3, Sds3~Sin3_corepress, Sds3~Sin3a_C
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0030336 - negative regulation of cell migration
GO:0045892 - negative regulation of DNA-templated transcription
GO:0070822 - Sin3-type complex
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 1098
Mm

1 328
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Mm
+ Hs
+ Dm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025