HitPredict

Interactor 1: FNDC5 (Q8K4Z2)
Fibronectin type III domain-containing protein 5 (Fibronectin type III repeat-containing protein 2) (Peroxisomal protein) (PeP) [Cleaved into: Irisin]
Gene: FNDC5

Interactor 2: TMED4 (Q8R1V4)
Transmembrane emp24 domain-containing protein 4 (Endoplasmic reticulum stress-response protein 25) (ERS25) (p24 family protein alpha-3) (p24alpha3) (p26)
Gene: TMED4

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30550785
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005783 - endoplasmic reticulum
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 209 Mm			1 227
+	Mm
		1225453 FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00		TMED9_MOUSE (1-227): 8.71e-90: 265: 76.21
+	Mm
		1225591 FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00		TMEDA_MOUSE (6-227): 1.19e-72: 221: 31.98
+	Mm
		88386 FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00		D3YZZ5_MOUSE (25-225): 2.1e-66: 206: 23.88
+	Mm
		1225751 FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00		TMED2_MOUSE (28-227): 2.59e-61: 192: 23.50
+	Mm
		1176469 FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00		TMED3_MOUSE (24-227): 1.01e-59: 189: 22.44
+	Mm
		1225552 FNDC5_MOUSE (1-209): 6.17e-146: 406: 100.00		TMED5_MOUSE (22-225): 8.05e-51: 166: 18.87