HitPredict

Interactor 1: Q647K1 (Q647K1)
Kelch-like 18
Gene: KLHL18

Interactor 2: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.50	0.407

Property	Details
Experiments	19615732
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 242 Hs			1 327
+	Hs
		1272553 KLHL4_HUMAN (89-242): 1.36e-28: 115: 21.61		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1198989 KLH12_HUMAN (110-240): 5.67e-26: 107: 32.82		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272580 KLHL8_HUMAN (100-242): 1.02e-24: 104: 24.48		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272601 KLH20_HUMAN (68-238): 6.76e-25: 104: 27.27		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272581 KLHL9_HUMAN (68-237): 6.64e-22: 95.9: 19.77		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272583 KLH13_HUMAN (61-242): 3.91e-21: 93.6: 18.42		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		320828 KLH18_HUMAN (68-242): 5.6e-21: 93.2: 18.33		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1235375 KLH10_HUMAN (89-239): 8.9e-21: 92.4: 23.53		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1247792 KLH24_HUMAN (65-238): 1.46e-15: 77.4: 19.43		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		131538 KLH20_HUMAN (68-238): 6.76e-25: 104: 27.27		EIF3F_HUMAN (10-306): 1.15e-110: 327: 22.07