HitPredict

Interactor 1: KLH10 (Q6JEL2)
Kelch-like protein 10
Gene: KLHL10

Interactor 2: CSN6 (Q7L5N1)
COP9 signalosome complex subunit 6 (SGN6) (Signalosome subunit 6) (JAB1-containing signalosome subunit 6) (MOV34 homolog) (Vpr-interacting protein) (hVIP)
Gene: COPS6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.73	0.60	0.662

Property	Details
Experiments	28514442, 33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 608 Hs			1 327
+	Hs
		1198989 KLH12_HUMAN (19-575): 9.32e-160: 471: 32.14		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272580 KLHL8_HUMAN (5-574): 8.09e-150: 447: 28.37		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272581 KLHL9_HUMAN (387-607): 1.04e-52: 192: 22.81		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272583 KLH13_HUMAN (387-607): 6.73e-52: 190: 21.93		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		320828 KLH18_HUMAN (461-608): 3.9e-34: 138: 28.00		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272601 KLH20_HUMAN (202-432): 1.39e-28: 122: 22.08		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272553 KLHL4_HUMAN (260-432): 3.33e-27: 118: 26.09		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1199991 KLH26_HUMAN (365-606): 1.14e-24: 110: 12.78		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1247792 KLH24_HUMAN (465-607): 2.08e-20: 97.2: 19.05		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		1272489 KLH23_HUMAN (341-574): 5.67e-17: 86.3: 29.63		CSN6_HUMAN (1-327): 1.81e-141: 404: 100.00
+	Hs
		131538 KLH20_HUMAN (202-432): 1.39e-28: 122: 22.08		EIF3F_HUMAN (10-306): 1.15e-110: 327: 22.07