HitPredict

Interactor 1: FZR3 (Q8LPL5)
Protein FIZZY-RELATED 3 (Cell cycle switch protein CCS52B)
Gene: FZR3

Interactor 2: CDC23 (Q9STS3)
Anaphase-promoting complex subunit 8 (Cell division cycle protein 23 homolog) (CDC23 homolog) (Cyclosome subunit 8)
Gene: APC8

Species: Arabidopsis thaliana

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	20706207
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005680 - anaphase-promoting complex GO:0007049 - cell cycle GO:0016567 - protein ubiquitination GO:0031145 - anaphase-promoting complex-dependent catabolic process GO:0051301 - cell division
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 481 At			1 579
+	At
		1258614 FZR1_ARATH (4-481): 6.07e-101: 312: 59.50		CDC23_ARATH (1-579): 1.24e-99: 315: 100.00
+	At
		1228243 FZR3_ARATH (1-481): 4.93e-112: 341: 100.00		APC7_ARATH (67-572): 2.35e-54: 195: 17.55
+	At
		1257910 FZR1_ARATH (4-481): 6.07e-101: 312: 59.50		APC7_ARATH (67-572): 2.35e-54: 195: 17.55
+	At
		71744 FZR3_ARATH (1-481): 4.93e-112: 341: 100.00		CDC16_ARATH (95-466): 6.03e-22: 101: 12.65
+	At
		1228161 FZR3_ARATH (1-481): 4.93e-112: 341: 100.00		CD27B_ARATH (346-579): 2.44e-18: 91.1: 14.53
+	Hs
		1160993 FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64		CTR9_HUMAN (143-565): 2.02e-28: 123: 10.90
+	Hs
		672926 FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64		CDC27_HUMAN (71-338): 8.44e-26: 114: 11.55
+	At
		71746 FZR1_ARATH (4-481): 6.07e-101: 312: 59.50		CDC16_ARATH (95-466): 6.03e-22: 101: 12.65
+	At
		1228163 FZR1_ARATH (4-481): 6.07e-101: 312: 59.50		CD27B_ARATH (346-579): 2.44e-18: 91.1: 14.53
+	Hs
		1117531 FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64		Q4KMX6_HUMAN (175-579): 3.86e-21: 99.2: 10.25
+	Hs
		1356137 FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64		APC7_HUMAN (175-579): 3.87e-21: 99.2: 10.25
+	Hs
		1356116 FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64		CDC23_HUMAN (275-579): 9.2e-10: 63.3: 12.91
+	Hs
		1023023 FZR1_HUMAN (17-467): 5.01e-97: 303: 50.64		CDC16_HUMAN (70-345): 2.04e-09: 62.2: 9.56
+	Hs
		175177 TBL1R_HUMAN (88-417): 2.59e-64: 218: 16.67		OGT1_HUMAN (2-223): 4.44e-17: 87.2: 9.91
+	Hs
		672800 WDR5_HUMAN (4-325): 1.72e-48: 171: 16.31		CDC27_HUMAN (71-338): 8.44e-26: 114: 11.55
+	Mm
		1246853 FBXW7_MOUSE (96-409): 1.8e-61: 214: 15.48		CDC16_MOUSE (70-345): 1.79e-09: 62.6: 9.22
+	Hs
		903589 WDR5_HUMAN (4-325): 1.72e-48: 171: 16.31		APC7_HUMAN (175-579): 3.87e-21: 99.2: 10.25
+	Rn
		1118803 CDC20_RAT (263-480): 9.56e-39: 148: 18.42		CDC27_RAT (341-579): 7.86e-26: 114: 14.05
+	Hs
		174768 WDR5_HUMAN (4-325): 1.72e-48: 171: 16.31		OGT1_HUMAN (2-223): 4.44e-17: 87.2: 9.91
+	Sc
		454920 AMA1_YEAST (131-458): 3.33e-38: 148: 30.61		CDC16_YEAST (212-578): 1.99e-13: 75.3: 10.27