HitPredict

Interactor 1: FTM (Q68CZ1)
Protein fantom (Nephrocystin-8) (RPGR-interacting protein 1-like protein) (RPGRIP1-like protein)
Gene: RPGRIP1L

Interactor 2: IBTK (Q9P2D0)
Inhibitor of Bruton tyrosine kinase (IBtk)
Gene: IBTK

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	26638075
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RCC1~RPGR1_C
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1315 Hs			1 1353
+	Hs
		1396194 RPGR1_HUMAN (241-1313): 0: 612: 31.37		IBTK_HUMAN (1-1353): 0: 1107: 100.00
+	Hs
		1228444 FTM_HUMAN (1-1315): 0: 875: 100.00		RPGR_HUMAN (300-710): 1e-34: 146: 10.07
+	Hs
		1369257 RPGR1_HUMAN (241-1313): 0: 612: 31.37		RPGR_HUMAN (300-710): 1e-34: 146: 10.07
+	Mm
		1424361 RPGR1_MOUSE (235-1313): 0: 618: 29.30		RPGR_MOUSE (22-298): 1.14e-28: 127: 17.18
+	Mm
		1225290 CCD18_MOUSE (31-785): 1.21e-20: 101: 9.45		SPOP_MOUSE (707-933): 2e-70: 243: 24.23
+	Mm
		1257413 MYH7_MOUSE (9-354): 8.27e-10: 66: 12.96		SPOP_MOUSE (707-933): 2e-70: 243: 24.23
+	Hs
		909122 NEK4_HUMAN (995-1144): 1.39e-28: 126: 34.84		RPGR_HUMAN (300-710): 1e-34: 146: 10.07
+	Hs
		342799 NEK4_HUMAN (995-1144): 1.39e-28: 126: 34.84		HERC2_HUMAN (28-245): 9.7e-32: 138: 22.87
+	Hs
		156941 CTRO_HUMAN (415-788): 1.39e-13: 78.3: 10.54		RCC1_HUMAN (47-414): 8.94e-38: 149: 19.54
+	Mm
		1196077 MYH10_MOUSE (310-794): 1.52e-16: 87.9: 11.38		HERC2_MOUSE (275-510): 3.91e-29: 129: 12.55
+	Hs
		157426 CTRO_HUMAN (415-788): 1.39e-13: 78.3: 10.54		HERC1_HUMAN (283-582): 7.23e-28: 125: 12.74
+	Hs
		587717 DESP_HUMAN (131-784): 1.24e-20: 101: 10.43		NEK8_HUMAN (249-427): 7.04e-12: 72.1: 20.42