HitPredict

Interactor 1: K1C40 (Q6A162)
Keratin, type I cytoskeletal 40 (Cytokeratin-40) (CK-40) (Keratin-40) (K40) (Type I hair keratin Ka36)
Gene: KRT40

Interactor 2: CCHCR (Q8TD31)
Coiled-coil alpha-helical rod protein 1 (Alpha-helical coiled-coil rod protein) (Putative gene 8 protein) (Pg8)
Gene: CCHCR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.726

Property	Details
Experiments	25416956, 29892012, 32296183, 33961781, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, two hybrid prey pooling approach, two hybrid array, validated two hybrid, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 431 Hs			1 782
+	Hs
		300440 KRT34_HUMAN (29-430): 8.4e-153: 440: 62.53		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		475642 K1C19_HUMAN (82-397): 4.57e-103: 313: 51.90		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		67555 K1C39_HUMAN (2-430): 3.24e-153: 444: 50.11		MYH7B_HUMAN (212-776): 1.65e-17: 90.1: 11.55
+	Hs
		476363 K1C16_HUMAN (85-412): 2.57e-96: 298: 51.52		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		618083 K1C15_HUMAN (88-401): 4.67e-95: 295: 52.38		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		49904 A1A4E9_HUMAN (80-411): 7.53e-95: 294: 50.75		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		566294 K1C13_HUMAN (80-411): 1.73e-94: 293: 50.75		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		475697 K1C19_HUMAN (82-397): 4.57e-103: 313: 51.90		MYO5C_HUMAN (90-633): 2e-50: 194: 20.00
+	Hs
		341817 K2C75_HUMAN (2-414): 7.13e-85: 271: 24.88		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		1350676 KRT35_HUMAN (2-427): 1.91e-84: 267: 59.35		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		300592 KRT36_HUMAN (7-409): 1.76e-82: 262: 63.28		CCHCR_HUMAN (1-782): 6.81e-66: 235: 100.00
+	Hs
		49879 A1A4E9_HUMAN (80-411): 7.53e-95: 294: 50.75		MYH1_HUMAN (266-781): 3.58e-19: 95.5: 10.94
+	Hs
		556836 K1C13_HUMAN (80-411): 1.73e-94: 293: 50.75		MYH1_HUMAN (266-781): 3.58e-19: 95.5: 10.94
+	Hs
		773163 K1C17_HUMAN (82-401): 2.07e-100: 307: 52.81		MYH10_HUMAN (415-782): 3.07e-12: 72.7: 10.05
+	Hs
		475644 K1C19_HUMAN (82-397): 4.57e-103: 313: 51.90		RBCC1_HUMAN (158-735): 1.99e-09: 63.7: 20.23
+	Hs
		772754 K1C17_HUMAN (82-401): 2.07e-100: 307: 52.81		MYH9_HUMAN (425-782): 5.8e-11: 68.5: 14.09
+	Hs
		1047454 K1C17_HUMAN (82-401): 2.07e-100: 307: 52.81		RBCC1_HUMAN (158-735): 1.99e-09: 63.7: 20.23
+	Hs
		556859 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		MYH1_HUMAN (266-781): 3.58e-19: 95.5: 10.94
+	Hs
		556936 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		MYH7_HUMAN (400-782): 2.15e-13: 76.6: 8.88
+	Hs
		535943 K1C40_HUMAN (1-431): 7.72e-82: 260: 100.00		MYH3_HUMAN (400-779): 2.03e-12: 73.5: 8.70