Interactor 1: DX39A (O00148)
ATP-dependent RNA helicase DDX39A (EC 3.6.4.13) (DEAD box protein 39) (Nuclear RNA helicase URH49)
Gene: DDX39A

Interactor 2: THOC2 (Q8NI27)
THO complex subunit 2 (Tho2) (hTREX120)
Gene: THOC2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 26496610
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains DEAD~Tho2, Helicase_C~Thoc2, Helicase_C~THOC2_N
Common GO terms GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0006406 - mRNA export from nucleus
and 1 others

more...

Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 427
Hs

1 1593
+ Hs
+ Hs
+ Dm
+ Sc
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025