HitPredict

Interactor 1: Q6FGM0 (Q6FGM0)
Endophilin-A2 (Endophilin-2)
Gene: SH3GL1

Interactor 2: Q8IZ09 (Q8IZ09)
SH3GL2 protein
Gene: SH3GL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.80	0.594

Property	Details
Experiments	25416956
Identification Methods	two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	BAR~BAR
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 368 Hs			1 279
+	Hs
		1408371 SH3G1_HUMAN (1-368): 5.78e-89: 274: 100.00		SH3G2_HUMAN (1-279): 7.48e-124: 358: 99.64
+	Hs
		1408389 SH3G3_HUMAN (1-368): 5.77e-87: 268: 66.30		SH3G2_HUMAN (1-279): 7.48e-124: 358: 99.64
+	Hs
		1232344 Q6FGM0_HUMAN (1-368): 5.78e-89: 274: 100.00		Q6FGM0_HUMAN (1-277): 2.93e-119: 347: 74.73
+	Hs
		1408370 SH3G1_HUMAN (1-368): 5.78e-89: 274: 100.00		SH3G1_HUMAN (1-277): 2.93e-119: 347: 74.73
+	Hs
		1408388 SH3G2_HUMAN (1-368): 1.68e-83: 259: 68.75		SH3G2_HUMAN (1-279): 7.48e-124: 358: 99.64
+	Mm
		1224161 SH3G2_MOUSE (1-368): 6.7e-83: 258: 69.02		SH3G2_MOUSE (1-279): 1.77e-122: 355: 98.93
+	Hs
		1408372 SH3G1_HUMAN (1-368): 5.78e-89: 274: 100.00		SH3G3_HUMAN (1-260): 4.31e-116: 339: 68.85
+	Hs
		1408407 SH3G3_HUMAN (1-368): 5.77e-87: 268: 66.30		SH3G3_HUMAN (1-260): 4.31e-116: 339: 68.85
+	Dm
		1345559 SH3G3_DROME (1-367): 4.38e-75: 238: 48.10		SH3G3_DROME (1-258): 1.37e-97: 292: 52.12
+	Hs
		1491061 SHLB1_HUMAN (10-363): 8.66e-69: 222: 25.28		SHLB1_HUMAN (10-277): 5.12e-95: 285: 25.63
+	Hs
		1447959 SHLB1_HUMAN (10-363): 8.66e-69: 222: 25.28		SHLB2_HUMAN (10-273): 6.98e-85: 261: 22.59
+	Hs
		1229262 SHLB1_HUMAN (10-363): 8.66e-69: 222: 25.28		RHG17_HUMAN (6-251): 2.46e-77: 253: 21.97
+	Hs
		1447947 SHLB2_HUMAN (10-363): 2.58e-58: 196: 22.34		SHLB2_HUMAN (10-273): 6.98e-85: 261: 22.59
+	Hs
		1165233 RHG44_HUMAN (6-251): 8.54e-47: 172: 22.22		RHG17_HUMAN (6-251): 2.46e-77: 253: 21.97
+	Dm
		1345547 Q8T389_DROME (2-365): 1e-49: 172: 21.32		Q8T389_DROME (10-274): 1.45e-80: 249: 24.54
+	Hs
		1165242 RHG44_HUMAN (6-251): 8.54e-47: 172: 22.22		3BP1_HUMAN (6-261): 7.67e-64: 214: 17.42