HitPredict

Interactor 1: LNX2 (Q8N448)
Ligand of Numb protein X 2 (Numb-binding protein 2) (PDZ domain-containing RING finger protein 1)
Gene: LNX2

Interactor 2: SYGP1 (Q96PV0)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: SYNGAP1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	29121065
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 690 Hs			1 1343
+	Hs
		1252417 LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Hs
		1271022 DLG3_HUMAN (352-689): 2.35e-43: 169: 21.53		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		100035 DLG1_MOUSE (306-689): 1.67e-38: 155: 21.85		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Hs
		942370 DLG4_HUMAN (412-690): 3.91e-33: 138: 20.07		SYGP1_HUMAN (1-1343): 0: 1004: 100.00
+	Mm
		99993 DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		100069 DLG2_MOUSE (390-690): 1.38e-32: 136: 19.02		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Mm
		99954 DLG3_MOUSE (416-689): 4.26e-29: 125: 22.30		SYGP1_MOUSE (1-1343): 0: 1003: 98.88
+	Rn
		677806 DLG4_RAT (412-690): 3.48e-33: 138: 20.07		SYGP1_RAT (1-1301): 0: 976: 98.85
+	Rn
		1144081 DLG3_RAT (397-689): 3.77e-29: 125: 20.88		SYGP1_RAT (1-1301): 0: 976: 98.85
+	Rn
		1337482 NHRF3_RAT (195-362): 7.36e-12: 70.4: 11.91		SYGP1_RAT (1-1301): 0: 976: 98.85
+	Mm
		1112545 DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07		DAB2P_MOUSE (97-1342): 0: 771: 46.89
+	Hs
		1256915 PARD3_HUMAN (473-672): 1.31e-14: 80.1: 29.13		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		1300689 MAGI1_HUMAN (558-670): 1.23e-10: 67.1: 25.83		NGAP_HUMAN (84-1341): 0: 732: 42.62
+	Hs
		809371 LNX1_HUMAN (12-690): 1.54e-118: 373: 45.07		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Mm
		1113181 DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07		IQGA2_MOUSE (216-848): 2.25e-120: 413: 13.94
+	Mm
		1143561 DLG4_MOUSE (412-690): 3.63e-33: 138: 20.07		RASL1_MOUSE (162-680): 4.92e-119: 392: 19.93
+	Hs
		809403 MAGI1_HUMAN (558-670): 1.23e-10: 67.1: 25.83		IQGA1_HUMAN (219-857): 5.95e-123: 421: 13.21
+	Hs
		598468 PTN13_HUMAN (71-499): 1.04e-21: 103: 12.73		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21
+	Hs
		598514 MAGI1_HUMAN (558-670): 1.23e-10: 67.1: 25.83		NF1_HUMAN (408-712): 3.21e-82: 301: 23.21