HitPredict

Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: TRAD1 (Q3UDK1)
TRAF-type zinc finger domain-containing protein 1 (Protein FLN29)
Gene: Trafd1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	0.60	0.608

Property	Details
Experiments	16221674, 18849341
Identification Methods	pull down, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008270 - zinc ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 530 Mm			1 580
+	Hs
		156175 TRAF6_HUMAN (1-530): 2.33e-139: 414: 87.93		TRAD1_HUMAN (1-575): 0: 1004: 76.22
+	Mm
		811902 TRAF2_MOUSE (38-508): 1.78e-101: 316: 25.75		TRAD1_MOUSE (1-580): 0: 1038: 100.00
+	Mm
		1190004 TRAF3_MOUSE (14-510): 1.65e-86: 279: 21.64		TRAD1_MOUSE (1-580): 0: 1038: 100.00
+	Mm
		811871 TRAF1_MOUSE (56-510): 4.79e-62: 210: 18.67		TRAD1_MOUSE (1-580): 0: 1038: 100.00
+	Hs
		1090714 TRAF2_HUMAN (38-508): 3.93e-101: 315: 25.55		XAF1_HUMAN (9-139): 5.48e-54: 187: 40.15
+	Hs
		1232903 TRI11_HUMAN (59-418): 2.77e-48: 175: 12.91		XAF1_HUMAN (9-139): 5.48e-54: 187: 40.15
+	Hs
		623389 RO52_HUMAN (56-417): 2.01e-42: 159: 12.88		XAF1_HUMAN (9-139): 5.48e-54: 187: 40.15
+	Hs
		1232904 TRI47_HUMAN (68-362): 1.45e-39: 154: 15.72		XAF1_HUMAN (9-139): 5.48e-54: 187: 40.15
+	Hs
		1232900 RN166_HUMAN (61-194): 9.37e-15: 75.7: 23.53		XAF1_HUMAN (9-139): 5.48e-54: 187: 40.15
+	Hs
		1232909 RN114_HUMAN (63-232): 2.74e-11: 65.3: 19.67		XAF1_HUMAN (9-139): 5.48e-54: 187: 40.15