HitPredict

Interactor 1: Q6NSK7 (Q6NSK7)
RIN3 protein
Gene: RIN3

Interactor 2: SRBS1 (Q9BX66)
Sorbin and SH3 domain-containing protein 1 (Ponsin) (SH3 domain protein 5) (SH3P12) (c-Cbl-associated protein) (CAP)
Gene: SORBS1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.50	0.417

Property	Details
Experiments	unassigned1973
Identification Methods	two hybrid fragment pooling approach
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 908 Hs			1 1292
+	Hs
		1347860 RIN3_HUMAN (1-908): 0: 586: 89.04		SRBS1_HUMAN (1-1292): 3.86e-164: 526: 100.00
+	Hs
		572836 Q6NSK7_HUMAN (1-908): 0: 666: 100.00		NCF1_HUMAN (701-1015): 4.89e-50: 184: 17.18
+	Hs
		594023 Q6NSK7_HUMAN (1-908): 0: 666: 100.00		NCK1_HUMAN (708-1005): 1.2e-49: 183: 18.27
+	Hs
		594053 RIN3_HUMAN (1-908): 0: 586: 89.04		NCK1_HUMAN (708-1005): 1.2e-49: 183: 18.27
+	Hs
		73623 RIN3_HUMAN (1-908): 0: 586: 89.04		B2R6S4_HUMAN (708-1005): 1.45e-49: 182: 18.27
+	Hs
		619080 RIN3_HUMAN (1-908): 0: 586: 89.04		PLCG1_HUMAN (394-880): 2.92e-43: 174: 11.75
+	Hs
		1154104 Q6NSK7_HUMAN (1-908): 0: 666: 100.00		ITSN1_HUMAN (492-1290): 3.41e-18: 93.3: 9.59
+	Hs
		1237986 Q6NSK7_HUMAN (1-908): 0: 666: 100.00		ITSN2_HUMAN (1040-1290): 7.97e-12: 72.5: 13.44
+	Hs
		1251252 RIN3_HUMAN (1-908): 0: 586: 89.04		DNMBP_HUMAN (796-1253): 3.42e-17: 89.9: 14.23
+	Hs
		1347881 RIN3_HUMAN (1-908): 0: 586: 89.04		ITSN2_HUMAN (1040-1290): 7.97e-12: 72.5: 13.44
+	Hs
		250295 RIN3_HUMAN (1-908): 0: 586: 89.04		VINEX_HUMAN (852-938): 9.34e-09: 61.9: 27.59
+	Rn
		204812 SYNJ1_RAT (153-642): 6.76e-44: 175: 15.79		SRBS2_RAT (335-924): 3.56e-14: 79.9: 13.09
+	Rn
		205732 SYNJ1_RAT (153-642): 6.76e-44: 175: 15.79		SH3G1_RAT (780-926): 2.12e-14: 78.4: 26.14
+	Hs
		1116655 RIN1_HUMAN (2-559): 5.29e-36: 148: 20.18		ITSN1_HUMAN (492-1290): 3.41e-18: 93.3: 9.59
+	Hs
		1116670 RIN1_HUMAN (2-559): 5.29e-36: 148: 20.18		SH3R1_HUMAN (220-850): 9.48e-10: 65.2: 13.22
+	Hs
		250244 RIN1_HUMAN (2-559): 5.29e-36: 148: 20.18		VINEX_HUMAN (852-938): 9.34e-09: 61.9: 27.59
+	Dm
		53899 Q9VHC3_DROME (16-158): 5.16e-29: 126: 21.77		A1Z866_DROME (254-848): 5.62e-14: 78.7: 11.89
+	Dm
		1286077 Q9VHC3_DROME (16-158): 5.16e-29: 126: 21.77		Q86P80_DROME (319-848): 1.01e-13: 77.9: 11.74
+	Hs
		250265 TENS2_HUMAN (3-217): 4.91e-32: 137: 19.33		VINEX_HUMAN (852-938): 9.34e-09: 61.9: 27.59
+	Hs
		250341 TENS1_HUMAN (25-213): 2.15e-25: 115: 14.98		VINEX_HUMAN (852-938): 9.34e-09: 61.9: 27.59