HitPredict

Interactor 1: KLH24 (Q6TFL4)
Kelch-like protein 24 (Kainate receptor-interacting protein for GluR6) (KRIP6) (Protein DRE1)
Gene: KLHL24

Interactor 2: KLH28 (Q9NXS3)
Kelch-like protein 28 (BTB/POZ domain-containing protein 5)
Gene: KLHL28

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 28514442, 33961781, 30190310
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB, BACK~Kelch_1
Common GO terms GO:0005737 - cytoplasm
GO:0031463 - Cul3-RING ubiquitin ligase complex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 600
Hs

1 571
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Service provided by Combinatics, Japan

Last updated: 11Aug2025