HitPredict

Interactor 1: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Interactor 2: CPAP (Q9HC77)
Centrosomal P4.1-associated protein (Centromere protein J) (CENP-J) (Centrosome assembly and centriole elongation protein) (LAG-3-associated protein) (LYST-interacting protein 1)
Gene: CPAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 1025 Hs			1 1338
+	Hs
		1250747 MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00		MY18A_HUMAN (505-1181): 3.94e-21: 103: 10.61
+	Hs
		772866 MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		1143271 PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		1234885 PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51		MY18A_HUMAN (505-1181): 3.94e-21: 103: 10.61
+	Hs
		772858 PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		587699 PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51		DESP_HUMAN (653-1103): 1.51e-09: 64.9: 15.82
+	Hs
		773112 MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45		MYH11_HUMAN (474-1212): 3.02e-26: 119: 9.91
+	Hs
		1414963 PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24		CP250_HUMAN (559-1267): 3.7e-11: 70.4: 9.54
+	Hs
		772814 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		PLEC_HUMAN (256-1192): 4.91e-28: 125: 6.72
+	Hs
		772647 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		MYH11_HUMAN (474-1212): 3.02e-26: 119: 9.91
+	Hs
		772645 MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Hs
		773110 MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45		MYH10_HUMAN (63-774): 1.93e-19: 97.4: 8.65
+	Hs
		772935 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		MY18A_HUMAN (505-1181): 3.94e-21: 103: 10.61
+	Hs
		772644 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		MYH9_HUMAN (570-1196): 7.95e-21: 102: 8.50
+	Mm
		563088 MYH8_MOUSE (146-958): 7.06e-17: 88.6: 9.39		MYH6_MOUSE (758-1216): 3.88e-11: 70: 10.56
+	Hs
		556902 MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35		MYH7_HUMAN (758-1203): 2.34e-11: 70.8: 11.14
+	Mm
		1037835 MYH1_MOUSE (237-931): 3.11e-16: 86.3: 8.91		MYH6_MOUSE (758-1216): 3.88e-11: 70: 10.56
+	Dm
		1404006 MYSN_DROME (457-975): 1.83e-17: 90.5: 15.79		MYSN_DROME (265-1063): 4.54e-09: 63.4: 14.63
+	Mm
		98073 MYH9_MOUSE (561-1013): 2.5e-17: 90.2: 12.80		DESP_MOUSE (653-1161): 7.07e-09: 63: 15.63