Interactor 1: TRPM4 (Q8TD43)
Transient receptor potential cation channel subfamily M member 4 (hTRPM4) (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (Melastatin-4)
Gene: TRPM4

Interactor 2: TRPM4 (Q8TD43)
Transient receptor potential cation channel subfamily M member 4 (hTRPM4) (Calcium-activated non-selective cation channel 1) (Long transient receptor potential channel 4) (LTrpC-4) (LTrpC4) (Melastatin-4)
Gene: TRPM4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.51 1.00 0.715

The method score is based on:

Property Details
Experiments 29217581, 29211723
Identification Methods 3D electron microscopy, electron microscopy 3D single particle reconstruction
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans, LSDAT_euk~LSDAT_euk
Common GO terms GO:0002250 - adaptive immune response
GO:0002407 - dendritic cell chemotaxis
GO:0002724 - regulation of T cell cytokine production
GO:0005227 - calcium-activated cation channel activity
GO:0005272 - sodium channel activity
and 36 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 1214
Hs

1 1214
+ Hs
+ Hs
+ Hs
+ Dr
+ Mm
+ Hs
+ Dm
+ Dm
+ Dm
+ Dm
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024