HitPredict

Interactor 1: DDX54 (Q8TDD1)
ATP-dependent RNA helicase DDX54 (EC 3.6.4.13) (ATP-dependent RNA helicase DP97) (DEAD box RNA helicase 97 kDa) (DEAD box protein 54)
Gene: DDX54

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12466272
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0030520 - estrogen receptor signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 881 Hs			1 530
+	Hs
		370067 DDX54_HUMAN (1-881): 0: 626: 100.00		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		377522 DDX54_HUMAN (1-881): 0: 626: 100.00		GCR_HUMAN (3-495): 1.12e-103: 330: 22.64
+	Hs
		757699 IF4A3_HUMAN (70-465): 7.91e-168: 495: 31.74		ESR2_HUMAN (1-530): 2.38e-157: 460: 100.00
+	Hs
		369113 IF4A3_HUMAN (70-465): 7.91e-168: 495: 31.74		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		181675 DDX3Y_HUMAN (4-484): 1.05e-153: 468: 25.05		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		370142 DDX17_HUMAN (44-531): 4.4e-141: 437: 26.78		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		368944 DDX5_HUMAN (7-516): 1.36e-140: 432: 25.48		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		369889 DDX46_HUMAN (3-736): 2.52e-135: 431: 23.01		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		133828 DDX3X_HUMAN (3-475): 2.2e-130: 407: 26.79		ESR1_HUMAN (9-529): 3.58e-138: 413: 44.56
+	Hs
		181691 DDX3Y_HUMAN (4-484): 1.05e-153: 468: 25.05		ERR3_HUMAN (60-499): 2.69e-106: 327: 30.29
+	Hs
		414517 DDX54_HUMAN (1-881): 0: 626: 100.00		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Mm
		509328 Q8BTS0_MOUSE (4-516): 1.29e-141: 435: 25.52		RARA_MOUSE (52-508): 5.87e-105: 324: 23.58
+	Hs
		571310 DDX5_HUMAN (7-516): 1.36e-140: 432: 25.48		NR4A1_HUMAN (7-501): 3.18e-101: 318: 25.30
+	Hs
		414435 DDX5_HUMAN (7-516): 1.36e-140: 432: 25.48		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		487641 DDX17_HUMAN (44-531): 4.4e-141: 437: 26.78		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487111 DDX5_HUMAN (7-516): 1.36e-140: 432: 25.48		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		487546 DDX46_HUMAN (3-736): 2.52e-135: 431: 23.01		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59
+	Hs
		571644 DDX5_HUMAN (7-516): 1.36e-140: 432: 25.48		NR2E1_HUMAN (149-408): 2.63e-35: 137: 31.82
+	Hs
		133840 DDX3X_HUMAN (3-475): 2.2e-130: 407: 26.79		PRGR_HUMAN (149-459): 2.26e-41: 161: 32.82
+	Hs
		133853 DDX3X_HUMAN (3-475): 2.2e-130: 407: 26.79		ANDR_HUMAN (149-407): 8.1e-38: 150: 32.59