HitPredict

Interactor 1: DMXL2 (Q8TDJ6)
DmX-like protein 2 (Rabconnectin-3)
Gene: DMXL2

Interactor 2: WDR7 (Q9Y4E6)
WD repeat-containing protein 7 (Rabconnectin-3 beta) (TGF-beta resistance-associated protein TRAG)
Gene: WDR7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.80	0.705

Property	Details
Experiments	12786944, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	WD40~WD40
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 3036 Hs			1 1490
+	Mm
		1207120 DMXL2_MOUSE (1-3036): 0: 4110: 92.66		WDR7_MOUSE (1-1490): 0: 1503: 93.31
+	Mm
		69661 B0V2P5_MOUSE (1-3036): 0: 4090: 91.87		WDR7_MOUSE (1-1490): 0: 1503: 93.31
+	Hs
		1377793 DMXL1_HUMAN (1-3033): 0: 3762: 54.63		WDR7_HUMAN (1-1490): 0: 1534: 98.26
+	Hs
		793026 KTNB1_HUMAN (2652-2927): 2.17e-48: 187: 14.49		LIS1_HUMAN (638-893): 1.28e-33: 137: 10.83
+	Dm
		1358845 WDS_DROME (2839-3034): 2.19e-54: 197: 14.21		WDS_DROME (669-863): 1.17e-29: 124: 8.72
+	Hs
		903551 NLE1_HUMAN (2490-2882): 2.3e-47: 180: 8.76		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		792935 LIS1_HUMAN (2834-3027): 4.43e-46: 175: 15.39		LIS1_HUMAN (638-893): 1.28e-33: 137: 10.83
+	Mm
		925836 LIS1_MOUSE (2834-3027): 4.3e-46: 175: 15.39		LIS1_MOUSE (638-893): 1.14e-33: 137: 10.83
+	Hs
		792949 LIS1_HUMAN (2834-3027): 4.43e-46: 175: 15.39		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		903418 FBXW7_HUMAN (2834-3032): 2.42e-40: 164: 12.12		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		1240442 POC1B_HUMAN (2835-3035): 5.02e-47: 179: 18.32		POC1A_HUMAN (632-896): 3.24e-26: 114: 7.06
+	Sc
		630844 NLE1_YEAST (2848-3036): 7.26e-45: 174: 15.66		NLE1_YEAST (635-933): 7.92e-27: 118: 12.30
+	Hs
		903349 WDR5B_HUMAN (2613-2833): 6.01e-37: 145: 9.74		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		1313645 KTNB1_HUMAN (2652-2927): 2.17e-48: 187: 14.49		KTNB1_HUMAN (19-211): 7.45e-09: 62.6: 14.87
+	Hs
		903077 WDR5_HUMAN (2477-2791): 2.08e-23: 106: 6.81		WDR5_HUMAN (16-237): 2.88e-33: 134: 13.90
+	Hs
		903174 WDR5_HUMAN (2477-2791): 2.08e-23: 106: 6.81		TBL3_HUMAN (14-216): 1.14e-25: 117: 16.75
+	Hs
		560857 GBB3_HUMAN (2838-3025): 1.85e-30: 127: 13.99		GBB3_HUMAN (458-718): 4.43e-20: 95.3: 15.09
+	Hs
		209416 WDR5_HUMAN (2477-2791): 2.08e-23: 106: 6.81		PLRG1_HUMAN (155-433): 1.44e-15: 83.7: 8.22