HitPredict

Interactor 1: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Interactor 2: LYAR (Q9NX58)
Cell growth-regulating nucleolar protein
Gene: LYAR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	17353931, 33961781
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0006364 - rRNA processing
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 379
+	Hs
		1291773 IMP4_HUMAN (2-272): 6.92e-91: 275: 17.56		LYAR_HUMAN (1-379): 6.59e-170: 480: 100.00
+	Hs
		1334495 RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83		LYAR_HUMAN (1-379): 6.59e-170: 480: 100.00
+	Hs
		1332923 RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88		LYAR_HUMAN (1-379): 6.59e-170: 480: 100.00
+	Hs
		1343147 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		LYAR_HUMAN (1-379): 6.59e-170: 480: 100.00
+	Sc
		733802 RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56		YC16_YEAST (1-58): 1.03e-17: 81.1: 50.85