HitPredict

Interactor 1: ASAP3 (Q8TDY4)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (Development and differentiation-enhancing factor-like 1) (Protein up-regulated in liver cancer 1)
Gene: ASAP3

Interactor 2: ASAP1 (Q9ULH1)
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein) (ADP-ribosylation factor-directed GTPase-activating protein 1) (ARF GTPase-activating protein 1) (Development and differentiation-enhancing factor 1) (DEF-1) (Differentiation-enhancing factor 1) (PIP2-dependent ARF1 GAP)
Gene: ASAP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.65 1.00 0.811

The method score is based on:

Property Details
Experiments 28514442, 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ank_2~Ank_2, Ank_2~ArfGap, Ank_2~SH3_9, ArfGap~ArfGap, ArfGap~PH, BAR_3~BAR_3, BAR_3~PH, PH~PH, PH~SH3_9
Common GO terms GO:0005096 - GTPase activator activity
GO:0005829 - cytosol
GO:0046872 - metal ion binding
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 903
Hs

1 1129
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+ Ce
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+ Sp
+ Mm
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Last updated: 15 Jul 2024