HitPredict

Interactor 1: BRX1 (Q8TDN6)
Ribosome biogenesis protein BRX1 homolog (Brix domain-containing protein 2)
Gene: BRIX1

Interactor 2: H2AW (Q9P0M6)
Core histone macro-H2A.2 (Histone macroH2A2) (mH2A2)
Gene: MACROH2A2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 353 Hs			1 372
+	Hs
		1334496 RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83		H2AW_HUMAN (1-372): 5.27e-152: 434: 100.00
+	Hs
		391809 BRX1_HUMAN (1-353): 6.13e-146: 418: 100.00		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		1332926 RPF2_HUMAN (106-247): 1.01e-31: 122: 22.88		H2AW_HUMAN (1-372): 5.27e-152: 434: 100.00
+	Hs
		1343150 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		H2AW_HUMAN (1-372): 5.27e-152: 434: 100.00
+	Hs
		470498 IMP4_HUMAN (2-272): 6.92e-91: 275: 17.56		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Hs
		470563 RPF1_HUMAN (13-269): 1.37e-72: 230: 20.83		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Sc
		392591 BRX1_YEAST (40-305): 1.92e-92: 279: 45.32		H2A2_YEAST (14-124): 2.55e-41: 143: 65.77
+	Sc
		392421 RPF1_YEAST (4-269): 5.6e-62: 201: 15.33		H2A2_YEAST (14-124): 2.55e-41: 143: 65.77
+	Hs
		391919 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		H2A1B_HUMAN (1-126): 6.65e-64: 201: 60.47
+	Hs
		470570 SSF1_HUMAN (54-228): 2.87e-21: 96.4: 15.22		H2A1_HUMAN (1-126): 6.37e-64: 201: 60.47
+	Sc
		392103 RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56		H2A1_YEAST (14-125): 3.15e-41: 143: 65.79
+	Sc
		392398 RPF2_YEAST (71-267): 1.62e-13: 72.5: 19.56		H2A2_YEAST (14-124): 2.55e-41: 143: 65.77