Protein: DECR
2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing], mitochondrial (EC 1.3.1.124) (2,4-dienoyl-CoA reductase [NADPH]) (4-enoyl-CoA reductase [NADPH]) (Short chain dehydrogenase/reductase family 18C member 1)

Gene: DECR, DECR1
Organism: Homo sapiens
Interactions: 77
UniProt ID: Q16698

Gene Ontology (top 5):
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005739 - mitochondrion
GO:0005759 - mitochondrial matrix
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

353816

PTTG1
Securin

4

0

High-throughput

0.667

High

333663

NDUAA
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial

3

1

High-throughput

0.667

High

1045346

TF65
Transcription factor p65

2

1

High-throughput

0.611

High

221857

CHM2A
Charged multivesicular body protein 2a

2

0

High-throughput

0.602

High

1162116

ECSIT
Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial

2

0

High-throughput

0.585

High

230330

CREB3
Cyclic AMP-responsive element-binding protein 3

2

0

High-throughput

0.547

High

911929

JAK3
Tyrosine-protein kinase JAK3

1

1

High-throughput

0.536

High

1162107

GEMI5
Gem-associated protein 5

1

1

High-throughput

0.536

High

1162121

EXOS5
Exosome complex component RRP46

1

1

High-throughput

0.536

High

619823

VCAM1
Vascular cell adhesion protein 1

2

1

High-throughput

0.521

High

140941

NOP56
Nucleolar protein 56

1

0

High-throughput

0.513

High

257119

CCD22
Coiled-coil domain-containing protein 22

1

0

High-throughput

0.513

High

282261

SAP30
Histone deacetylase complex subunit SAP30

1

0

High-throughput

0.513

High

365758

KAD1
Adenylate kinase isoenzyme 1

1

0

High-throughput

0.513

High

384423

CRYAA
Alpha-crystallin A chain

1

0

High-throughput

0.513

High

447070

NPM
Nucleophosmin

1

0

High-throughput

0.513

High

659489

CRCM
Colorectal mutant cancer protein

1

0

High-throughput

0.513

High

693767

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.513

High

913333

MSH6
DNA mismatch repair protein Msh6

1

0

High-throughput

0.513

High

913502

KIF11
Kinesin-like protein KIF11

1

0

High-throughput

0.513

High

947386

NALP5
NACHT, LRR and PYD domains-containing protein 5

1

0

High-throughput

0.513

High

1059229

TISB
mRNA decay activator protein ZFP36L1

1

0

High-throughput

0.513

High

1162105

AF1L1
Actin filament-associated protein 1-like 1

1

0

High-throughput

0.513

High

1162110

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.513

High

1162119

COMD5
COMM domain-containing protein 5

1

0

High-throughput

0.513

High

1162125

BAIP2
BAR/IMD domain-containing adapter protein 2

1

0

High-throughput

0.513

High

1162126

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

422190

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.501

High

396212

ESR1
Estrogen receptor

1

8

High-throughput

0.500

High

626962

FST
Follistatin

1

1

High-throughput

0.489

High

169572

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

0

Small-scale

0.480

High

132074

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

2

High-throughput

0.479

High

227574

SPOP
Speckle-type POZ protein

1

2

High-throughput

0.479

High

372156

MYC
Myc proto-oncogene protein

1

3

High-throughput

0.479

High

400902

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

4

High-throughput

0.479

High

412007

NTRK1
High affinity nerve growth factor receptor

1

2

High-throughput

0.479

High

413932

P53
Cellular tumor antigen p53

1

2

Small-scale

0.479

High

447769

TPM3
Tropomyosin alpha-3 chain

1

1

High-throughput

0.479

High

482491

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.479

High

767229

MERL
Merlin

1

1

High-throughput

0.479

High

828784

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

867166

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.479

High

1015469

RHOG
Rho-related GTP-binding protein RhoG

1

1

High-throughput

0.479

High

1089209

TRI26
Tripartite motif-containing protein 26

1

3

Small-scale

0.479

High

1104196

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

1

High-throughput

0.479

High

1162102

A16L1
Autophagy-related protein 16-1

1

5

High-throughput

0.479

High

1162108

ESR2
Estrogen receptor beta

1

8

High-throughput

0.479

High

1162123

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

247935

NUPR1
Nuclear protein 1

1

0

High-throughput

0.458

High

472778

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

615547

NELFE
Negative elongation factor E

1

0

High-throughput

0.458

High

651347

CBL
E3 ubiquitin-protein ligase CBL

1

0

High-throughput

0.458

High

879147

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

934681

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

1138259

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.458

High

1162103

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1162106

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1162109

FBX32
F-box only protein 32

1

0

Small-scale

0.458

High

1162112

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1162113

RANB9
Ran-binding protein 9

1

0

Small-scale

0.458

High

1162122

ANLN
Anillin

1

0

High-throughput

0.458

High

1162101

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

2

High-throughput

0.445

High

389405

FINC
Fibronectin

1

1

High-throughput

0.437

High

565400

ITA4
Integrin alpha-4

1

1

High-throughput

0.437

High

1162104

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

1162117

ACE2
Angiotensin-converting enzyme 2

1

1

High-throughput

0.437

High

1162124

HECD1
E3 ubiquitin-protein ligase HECTD1

1

3

High-throughput

0.437

High

354708

PAK4
Serine/threonine-protein kinase PAK 4

1

0

High-throughput

0.426

High

942649

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

0

High-throughput

0.426

High

960371

SMS
Somatostatin

1

0

Small-scale

0.426

High

1098000

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.426

High

1162111

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.426

High

1162118

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

1162115

F118B
Protein FAM118B

2

0

High-throughput

0.328

High

1162114

SH3G3
Endophilin-A3

2

0

High-throughput

0.298

High

106016

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

1162120

DDX24
ATP-dependent RNA helicase DDX24

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025