HitPredict

Interactor 1: H32 (Q71DI3)
Histone H3.2 (H3-clustered histone 13) (H3-clustered histone 14) (H3-clustered histone 15) (Histone H3/m) (Histone H3/o)
Gene: H3C15

Interactor 2: PF21A (Q96BD5)
PHD finger protein 21A (BHC80a) (BRAF35-HDAC complex protein BHC80)
Gene: PHF21A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.50	1.00	0.710

Property	Details
Experiments	17687328
Identification Methods	pull down, x-ray crystallography
Interaction Type	direct interaction, association

Property	Details
Interacting Pfam domains	Histone~PHD
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0003677 - DNA binding GO:0003682 - chromatin binding GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 136 Hs			1 680
+	Hs
		998946 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		TRI33_HUMAN (2-648): 5.13e-88: 299: 16.08
+	Hs
		180775 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		TIF1A_HUMAN (2-647): 2.12e-79: 275: 14.56
+	Hs
		998913 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM5B_HUMAN (147-656): 1.24e-63: 231: 14.04
+	Hs
		711809 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		KDM5A_HUMAN (211-656): 2.13e-53: 201: 16.59
+	Hs
		998921 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		BAZ2A_HUMAN (4-648): 2.66e-53: 200: 11.71
+	Hs
		711825 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		KDM5A_HUMAN (211-656): 2.13e-53: 201: 16.59
+	Hs
		998920 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		BAZ2B_HUMAN (2-648): 1.04e-44: 175: 12.38
+	Hs
		998577 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD5_HUMAN (255-617): 1.44e-43: 171: 16.79
+	Hs
		998324 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51
+	Hs
		1161955 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CHD5_HUMAN (255-617): 1.44e-43: 171: 16.79
+	Hs
		1132727 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		CHD4_HUMAN (255-650): 3.89e-43: 170: 14.51
+	Hs
		998258 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		CHD3_HUMAN (297-617): 2.53e-41: 164: 16.57
+	Hs
		998715 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		RSF1_HUMAN (156-578): 5.97e-34: 141: 16.59
+	At
		947417 H33_ARATH (1-136): 7.79e-62: 187: 96.32		ATXR6_ARATH (459-615): 9.09e-34: 134: 22.22
+	Hs
		231129 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		AIRE_HUMAN (472-538): 1.24e-19: 94.9: 43.06
+	Hs
		231147 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		AIRE_HUMAN (472-538): 1.24e-19: 94.9: 43.06
+	Mm
		999040 H31_MOUSE (1-136): 3.1e-62: 188: 99.27		AIRE_MOUSE (485-532): 2.64e-16: 84.5: 50.00
+	Hs
		998706 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		PHF12_HUMAN (462-541): 2e-13: 76: 31.71
+	Hs
		355489 H31_HUMAN (1-136): 3.1e-62: 188: 99.27		NSD2_HUMAN (423-540): 6.19e-09: 61.5: 20.00
+	Hs
		355534 H31T_HUMAN (1-136): 1.38e-61: 186: 96.32		NSD2_HUMAN (423-540): 6.19e-09: 61.5: 20.00