HitPredict

Interactor 1: AIRE (O43918)
Autoimmune regulator (Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein) (APECED protein)
Gene: AIRE

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.61	1.00	0.786

Property	Details
Experiments	18292755
Identification Methods	pull down, unspecified method, affinity chromatography technology, x-ray crystallography, nuclear magnetic resonance, isothermal titration calorimetry, fluorescence technology
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	Histone~PHD
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 545 Hs			1 136
+	Hs
		231147 AIRE_HUMAN (1-545): 1.25e-134: 403: 100.00		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Mm
		999040 AIRE_MOUSE (16-544): 2.94e-123: 374: 71.72		H31_MOUSE (1-136): 1.85e-62: 189: 100.00
+	Hs
		320320 PHF14_HUMAN (126-484): 3.62e-44: 169: 16.71		H31_HUMAN (1-136): 1.85e-62: 189: 100.00
+	Hs
		320324 PHF14_HUMAN (126-484): 3.62e-44: 169: 16.71		H33_HUMAN (1-136): 1.45e-61: 186: 96.32
+	Hs
		659248 SP100_HUMAN (3-296): 1.82e-36: 146: 13.81		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Hs
		998435 JADE1_HUMAN (120-523): 6.96e-35: 141: 12.28		H31_HUMAN (1-136): 1.85e-62: 189: 100.00
+	Hs
		1234186 JADE1_HUMAN (120-523): 6.96e-35: 141: 12.28		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Hs
		1161989 PF21A_HUMAN (130-352): 7.18e-33: 135: 23.38		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Hs
		1017092 PF21A_HUMAN (130-352): 7.18e-33: 135: 23.38		H33_HUMAN (1-136): 1.45e-61: 186: 96.32
+	Hs
		1258907 PF21A_HUMAN (130-352): 7.18e-33: 135: 23.38		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Hs
		998324 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		H31_HUMAN (1-136): 1.85e-62: 189: 100.00
+	Hs
		1132727 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Hs
		1016866 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		H33_HUMAN (1-136): 1.45e-61: 186: 96.32
+	Hs
		1132776 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		H32_HUMAN (1-136): 3.8e-61: 186: 99.27
+	Mm
		59101 CHD5_MOUSE (92-496): 2.14e-30: 128: 14.91		H33_MOUSE (1-136): 1.45e-61: 186: 96.32
+	Hs
		320315 PHF14_HUMAN (126-484): 3.62e-44: 169: 16.71		CENPA_HUMAN (9-133): 7.51e-45: 144: 50.00
+	Sc
		963711 RCO1_YEAST (143-476): 9.31e-35: 140: 14.89		H3_YEAST (1-136): 7.41e-56: 172: 88.97
+	Hs
		998577 CHD5_HUMAN (288-504): 6.09e-28: 121: 17.41		H31_HUMAN (1-136): 1.85e-62: 189: 100.00
+	Hs
		1161955 CHD5_HUMAN (288-504): 6.09e-28: 121: 17.41		H31T_HUMAN (1-136): 9.24e-62: 187: 97.06
+	Hs
		1132762 CHD4_HUMAN (74-489): 2.07e-30: 128: 13.43		H3C_HUMAN (1-136): 8.62e-59: 179: 93.38