HitPredict

Interactor 1: ASB5 (Q8WWX0)
Ankyrin repeat and SOCS box protein 5 (ASB-5)
Gene: ASB5

Interactor 2: ASB1 (Q9Y576)
Ankyrin repeat and SOCS box protein 1 (ASB-1)
Gene: ASB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24337577
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank~Ank_2, Ank_2~Ank_2, Ank_2~SOCS_box
Common GO terms	GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0035556 - intracellular signal transduction
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 329 Hs			1 335
+	Hs
		1264016 ASB9_HUMAN (69-328): 1.24e-91: 276: 52.69		ASB13_HUMAN (3-183): 1.38e-46: 160: 23.20
+	Hs
		862028 ANK2_HUMAN (1-252): 3.84e-70: 238: 23.26		DAPK1_HUMAN (3-163): 5.2e-40: 151: 18.63
+	Mm
		103608 ANK2_MOUSE (1-252): 1.38e-69: 237: 23.26		ANK3_MOUSE (200-331): 1.05e-20: 95.3: 10.61
+	Hs
		883487 RIPK4_HUMAN (2-176): 2.35e-39: 149: 18.99		ANK2_HUMAN (3-163): 6.4e-46: 169: 24.85
+	Mm
		103591 ANK3_MOUSE (1-252): 1.83e-64: 222: 22.87		ANK3_MOUSE (200-331): 1.05e-20: 95.3: 10.61
+	Hs
		965154 Q9H4D1_HUMAN (2-176): 9.18e-39: 147: 18.99		ANK2_HUMAN (3-163): 6.4e-46: 169: 24.85
+	Hs
		166869 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		TNKS1_HUMAN (4-244): 2.61e-50: 181: 20.39
+	Hs
		166969 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		ANR44_HUMAN (79-322): 1.2e-47: 173: 16.79
+	Hs
		166913 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		ANK2_HUMAN (3-163): 6.4e-46: 169: 24.85
+	Hs
		862012 DAPK1_HUMAN (129-328): 1.34e-36: 141: 17.65		DAPK1_HUMAN (3-163): 5.2e-40: 151: 18.63
+	Hs
		166971 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		ANR52_HUMAN (2-165): 9.73e-30: 121: 22.02
+	Hs
		167014 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		TNKS2_HUMAN (115-325): 3.4e-27: 114: 15.39
+	Hs
		883691 RIPK4_HUMAN (2-176): 2.35e-39: 149: 18.99		ASB3_HUMAN (150-291): 1.35e-09: 61.2: 19.72
+	Hs
		883496 RIPK4_HUMAN (2-176): 2.35e-39: 149: 18.99		ANK3_HUMAN (3-56): 7.49e-09: 59.5: 18.52
+	Hs
		1330905 Q9H4D1_HUMAN (2-176): 9.18e-39: 147: 18.99		ASB3_HUMAN (150-291): 1.35e-09: 61.2: 19.72
+	Hs
		1021462 Q9H4D1_HUMAN (2-176): 9.18e-39: 147: 18.99		ANK3_HUMAN (3-56): 7.49e-09: 59.5: 18.52
+	Hs
		257652 ANKH1_HUMAN (5-189): 9.39e-35: 136: 16.75		ANR17_HUMAN (3-59): 2.58e-12: 69.9: 19.30
+	Hs
		166919 ANR28_HUMAN (168-327): 1.91e-31: 126: 23.60		ANK3_HUMAN (3-56): 7.49e-09: 59.5: 18.52